As one of only three large-scale, NIH funded genome centers in the United States, the Genome Institute at Washington University School of Medicine in St. Louis has been a large contributer to cancer research and the research of child illnesses since it was founded in 1993.
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2012 was a big year for the science of snipping DNA to introduce genetic changes into a cell, also known as genome editing. Though Science magazine hailed two new techniques for selectively cutting and pasting DNA in the field of genome engineering as together constituting one of the Top 10 scientific breakthroughs of the year, those methods may already have been surpassed by researchers at the University of California Berkeley using RNA and a single protein. Faster, simpler, and cheaper, the UCB team led by Dr. Jennifer Doudna published initial results of their work genetically modifying bacteria using the RNA-based DNA cleavage technique last summer. The response from the the life science community was extremely positive, with reviews calling it a "tour de force" and a "a real hit," according to the latest press release. Now three more papers are coming out based on the work of the Doudna Lab showing that the RNA programming technique using a bacterial enzyme known as Cas9 is equally effective in making alterations to human genes.
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An historic collaboration between the University of California Davis and China's BGI, the world’s largest genomics organization, has dramatically increased the University's genome sequencing capabilities and promises to open up altogether new research opportunities in the life sciences community with genomic studies of plants, animals, humans and microbes. The new joint endeavor is called BGI@UC Davis and will benefit both UCD and China's first citizen-managed, non-profit research institution.
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In the search for early life we are going where we have never gone before...with newly-funded astrobiology research at the University of Illinois.
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The summer of 2012 is set to go down as one of the driest and worst years for US farmers, but it's proving to be an excellent season for fruit science, especially at the University of Arizona, Tucson. In June we saw the sequencing of the tomato genome (technically a fruit), which was a breakthrough in genetics research. The Arizona Genomics Institute has now cracked another complex code: the genome of the banana.
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