The National Institute of Health (NIH) awarded Washington University in St. Louis over $1.4 million in grant funding to support their School of Medicine’s Diabetic Research Center. This award was administered through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) as it has been for the last 38 years. The funding will help support the Diabetic Research Center (DRC) and their life science labs. The DRC's mission is to “support and enhance research in diabetes and related metabolic diseases” through Biomedical Research Core services as well as the Pilot and Feasibility Program.
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Researchers at University of California San Diego School of Medicine were recently awarded two Type 1 Diabetes Special Statutory Funding Program grants from the NIH, totaling more than $5 million in research funding.
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The University of Illinois at Chicago received a two-year, $475,000 grant to study a new treatment for type 1 diabetes that might help protect the pancreas. This promising new treatment would involve using two protein molecules to reduce the damage caused by the body’s autoimmune response. The research led by Dr. Bellur S. Prabhaker, Professor of Microbiology and Immunology at UIC, could eventually free many diabetes patients from the rigors of daily insulin injections.
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Two University of Wisconsin-Madison researchers won 2016 Shaw Scientist Awards. This program has supported early research efforts pursuing promising ideas in biochemistry, biological sciences and cancer research for over thirty years. The award given by the Greater Milwaukee foundation includes a $200,000 grant for each recipient to be used as seed money for his or her respective projects. Feyza Engin, Ph.D., Assistant Professor of Biomolecular Chemistry, is researching type 1 diabetes. Srivatsan Raman, Ph.D., Assistant Professor of Biochemistry, is conducting research into the properties that allow proteins to change shape.
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Diabetes encompasses a group of metabolic disorders that result in chronically elevated blood sugar levels. If untreated, these diseases can result in serious complications such as ketoacidosis, heart disease, kidney failure, and stroke. The most common type of diabetes is type II diabetes, which accounts for 90-95% of cases (a recent Philadelphia study helped us gain further insight into why type II diabetes occurs). The incidence of type I diabetes is much lower, accounting for just 5-10% of cases. However, while type II diabetes can resolve on its own with changes in diet and exercise habits, type I is considered incurable. Now, a new study from the University of Colorado, Anschutz Medical Campus has identified a new class of antigens that may be a factor in the development of the disease.
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The National Institutes of Health (NIH) recently launched a new network of institutions - called the Centers for Common Disease Genomics (CCDG) - which will study common conditions such as heart disease, stroke, diabetes, and autism to see how genetics and DNA contribute to the risk of these diseases. The McDonnell Genome Institute at Washington University in St. Louis is one of four institutions involved in this network and will be receiving $60 million over the next four years to study genomics and common diseases.
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When the level of blood glucose, also called blood sugar, rises after a meal, the pancreas responds by releasing insulin into the bloodstream. Insulin helps cells throughout the body absorb glucose from the bloodstream and use it for energy.
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Insulin is a vital hormone that plays a major role in the metabolism: without insulin, humans would not be able to break down carbohydrates or digest food for energy. Insulin lowers blood glucose levels, stores excess glucose as glycogen and reduces glucose production in the liver. Many people, however, have trouble using insulin effectively. Forms of insulin resistance can lead to pre-diabetes or type 2 diabetes, as well as other serious health problems.
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Researchers at Georgetown University conducted a study that suggests that undiagnosed pre-diabetes occurs at higher rate than was previously thought in people with Alzheimer’s disease. Dr. R. Scott Turner, director of the Georgetown University Medical Center’s Memory Disorders Program, brought people into the study who had mild to moderate Alzheimer’s disease so that he could investigate resveratrol, a compound found in red grapes and red wine. Resveratrol is thought to mimic the effects of a low calorie diet. When the study began, Dr. Turner said he was shocked by how many of the study’s participants had pre-diabetes.
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