Researchers at the University of Minnesota, Twin Cities have created a new lab-grown blood vessel replacement that is composed completely of biological materials, yet contains no living cells at implantation. It is the first-of-its-kind nonsynthetic, decellularized graft that becomes repopulated with the recipient’s own cells after implanted. This discovery could help tens of thousands of kidney dialysis patients each year. It could also be adapted for use as coronary and peripheral bypass blood vessels and tubular heart valves in the future.
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According to the Centers for Disease Control and Prevention 153 people in the U.S. die from injuries that include a traumatic brain injury (TBI) every day. Currently, there are no effective treatments for moderate-to-severe TBIs. So those who do survive their injuries often live the rest of their lives with impaired thinking, memory, or movement. TBIs can also lead to personality and emotional changes. However, research being conducted at the University of Georgia, Athens (UGA) might lead to a treatment that could significantly improve the prognosis of those with brain injuries. This promising research into a glue-like substance for the brain recently won a $1.5 NIH grant award.
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UC Davis Medical Center’s Mind Institute was one of five institutes in the nation to win the NIH’s Autism Centers of Excellence Award (ACE). The $12 million, five year grant, will be used for the creation of the “Center for the Development of Phenotype-based Treatments of Autism Spectrum Disorder.” This new center will take a personalize approach to addressing autism spectrum disorder (ASD) treatment based on a child’s behavioral and biological characteristics. The goal will be to identify and tailor treatments that improve the quality of life for those with ASD.
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Total research and development expenditures for the University of Georgia, Athens (UGA) reached an all-time high of $458 million. This is a 31% increase in R&D expenditures since the 2013 fiscal year. Over the past three years, externally funded research activities have climbed by 37% to reach $198 million in fiscal 2017. These expenditures are funded in part by federal grants and contracts. For example: in the first seven months of 2017 the University received 96 research project grants from the National Institute of Health (NIH). They total $37.2 million. The rest of their research funding comes from foundations, corporations, as well as the state of Georgia.
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According to an article for UAB News, 40% of individuals infected with HIV are not currently receiving antiretroviral therapy, which means their disease is not suppressed. The University of Alabama, Birmingham’s Center for AIDS Research recently partnered with state and local agencies in signing the Paris Declaration to eliminate the spread of HIV/AIDS by 2030. Birmingham is the 13th U.S. city to commit to achieving the Declaration’s goals.
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For the sixth year in a row, UC San Francisco was the top public recipient of biomedical research grants from the National Institutes of Health (NIH). Overall, UCSF researchers were awarded $577.6 million in NIH grants and contracts in 2016. This was a 3 percent increase over 2015, which is consistent with UCSF’s average annual increase over the past five years.
(Image courtesy of Wikimedia Commons)
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So far in 2017 the National Institute on Health has awarded the University of Pittsburgh over $113M in research project grants. This funding supports 296 separate projects. The top six grants were awarded to the university’s School of Medicine.
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When it comes to research the University of Minnesota has a lot going for it. Their 4,000 faculty include members of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine, as well as the American Academy of Arts and Sciences. U of M ranks 8th among public universities in research spending, with more than $870 million spent annually. In 2016, over $243M of that research funding was awarded by the National Institute of Health.
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Thus far in 2017, the University of California Los Angeles has received over $6.8 million in funding from the National Heart Lung and Blood Institute (NHLBI). This funding has been awarded through multiple grants intended to support cardiovascular research.
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Anti-fungal research at New York's Stony Brook University earned $6 million in grants from the National Institute of Health. Dr. Maurizio del Poeta’s breakthrough in attacking deadly fungus came from a recent research project that yielded an unexpected result that might lead to a vaccine. He and his team were searching for a gene that would metabolize a fungal sphingolipid. Instead, the gene he mutated caused mice that were exposed to it to become resistant to fungal infections. In an article on the Stony Brook University’s news site, Dr. Poeta said , “We think that this discovery will open the road to a new vaccination strategy against fungi.”
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