On average, 20 people die each day while waiting for an organ transplant, according to the United Network of Organ Sharing. However, scientists at the University of Minnesota envision a day when organ transplants from donors will no longer be necessary. Instead, failing organs will be replaced with ones created by specialized 3D printers. In a giant step toward that goal, researchers have manufactured lifelike artificial organ models using a custom-built 3D printer. These models mimic the exact anatomical structure, mechanical properties, as well as the look and feel of real organs. This research project is supported by two, five-year NIH grants that total over $2.6 million.
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Researchers at the University of Minnesota, Twin Cities have created a new lab-grown blood vessel replacement that is composed completely of biological materials, yet contains no living cells at implantation. It is the first-of-its-kind nonsynthetic, decellularized graft that becomes repopulated with the recipient’s own cells after implanted. This discovery could help tens of thousands of kidney dialysis patients each year. It could also be adapted for use as coronary and peripheral bypass blood vessels and tubular heart valves in the future.
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When it comes to research the University of Minnesota has a lot going for it. Their 4,000 faculty include members of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine, as well as the American Academy of Arts and Sciences. U of M ranks 8th among public universities in research spending, with more than $870 million spent annually. In 2016, over $243M of that research funding was awarded by the National Institute of Health.
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Acute lymphoblastic leukemia (ALL) is the most common type of childhood cancer, affecting nearly 6 thousand children in the US annually. Recently, a possible relationship has been identified, which may provide valuable insight into why this cancer develops and how to prevent it.
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