Two researchers in UC San Diego’s Division of Biological Sciences were selected as Pew biomedical scholars for 2017. Microbiologist, Rachel Dutton Ph.D. and physicist, Elizabeth Villa, Ph.D. were each awarded flexible funding that may be used at their discretion for personnel, lab equipment, supplies, or travel directly related to their research. Dutton and Villa were selected this as part of this year’s group of 22 exceptional early-career researchers who will receive support for their foundational research.
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In March, the National Cancer Institute (NCI) approved a $3.7 million, five-year grant to extend Dr. Eric Chow’s research into improving treatment of cardiovascular risk factors in childhood cancer survivors. Dr. Chow is a clinical researcher, epidemiologist, and pediatric oncologist at Fred Hutchinson Cancer Research Center in Seattle, Washington. This is one of two research grants to be awarded to Dr. Chow by the National Cancer Institute. The NCI also chose to extend Dr. Chow’s study of the long-term efficacy of a medication meant to minimize or prevent heart injury in pediatric patients going through chemotherapy. This $2.7 million in research funding will allow for four more years of studies regarding the use of dexrazoxane in pediatric cancer patients.
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Electric catfish is the common name for the catfish that belong to the Malapteruridae family. Several species of this family can produce an electric shock of up to 350 volts. To do this the use electric organ known as electroplaques. This electrogenic organ is derived from anterior body musculature and lines the body cavity. Electric catfish are found in tropical Africa and the Nile River. Some species feed primarily on other fish, incapacitating their prey with electric discharges. However the majority are generalist bottom feeders. The largest species can grow to up four feet long.
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Columbia University Medical Center’s new, state-of-the-art medical and graduate education building was completed in time to open for the fall term. Construction of the Roy and Diana Vagelos Education Center began in September of 2013. The building was designed to reshape the look and feel of the Medical Center campus and to create spaces that facilitate the development of skills essential for modern medical practice. This 100,000-square-foot, glass, concrete and steel center’s most distinguishing feather is a network of social and study spaces distributed along an exposed, interconnected vertical staircase, known as the “Study Cascade” which extends the height of the 14 story building.
(Image courtesy of Jenny Gorman via Columbia University Media)
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For the 2016 fiscal year budget, and Congress increased government funding on research for Alzheimer's by $350 million. That was a 50% increase over the previous year. The Alzheimer’s Association estimates that the National Institutes of Health would need $2 billion a year to maximize the chances of curing or preventing the disease by 2025. This year’s increase puts the NIH on track to reach that goal. Alzheimer's Disease is the most common form of dementia and this increased science research funding it is already beginning to pay off.
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Dr. Robert Darnell, Professor of Cancer Biology and Head of the Laboratory of Molecular Neuro-Oncology at Rockefeller University, received a $1.1 million grant from the NIH’s National Institute of Neurological Disorders and Stroke.
This research funding will support his lab’s new approach to studying diseases of the brain through modern biotech services and more efficient informatics. He and his lab will work on harnessing the power of molecular biology to define therapeutic targets for several different types of brain diseases. Researchers will do this by combining the latest technological advances modern science has brought to neuroscience with new computational approaches.
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The National Institute of Health (NIH) awarded Washington University in St. Louis over $1.4 million in grant funding to support their School of Medicine’s Diabetic Research Center. This award was administered through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) as it has been for the last 38 years. The funding will help support the Diabetic Research Center (DRC) and their life science labs. The DRC's mission is to “support and enhance research in diabetes and related metabolic diseases” through Biomedical Research Core services as well as the Pilot and Feasibility Program.
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The California Institute for Regenerative Medicine (CIRM) awarded two scientists at UC San Diego $2 million each for their innovative research. The first award went to Alysson R. Muotri, PhD, professor in the UC San Diego School of Medicine departments of Pediatrics and Cellular and Molecular Medicine. The funding will support studies of new treatments for Zika. The second award went to Dan Kaufman, MD, PhD, professor of medicine in the Division of Regenerative Medicine. This funding will support the creation an “off-the-shelf immunotherapy” using NK cells to treat refractory or resistant tumors, such as ovarian cancer.
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The National Institute of Health (NIH) awarded the University of Georgia a $2.27 Million grant to study a powerful gene editing tool known as CRISPR-Cas. In nature, CRISPR-Cas is a defense mechanism that single-celled organisms such as bacteria use to ward off attacks from viruses and other invaders. For scientists the CISPR-Cas9 system holds a potential tool to edit precise sequences of DNA and silence the genes that predispose some people to diseases such as cancer, diabetes, cardiovascular disorders and mental illness.
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Researchers at UCLA believe using the patient’s own cells to create stem cells for therapeutic purposes is the future of medicine. A recently published study by scientists at UCLA demonstrates how specialized proteins change the cellular characteristics of skin cells to create induced pluripotent stem cells. These stem cells have the ability to turn into any cell type within the body. Also at UCLA, a clinical trial which uses the baby’s own blood-forming stem cells to treat the immune deficiency condition ADA-SCID, better known as “bubble baby disease,” was recently awarded a $20M grant from the California Institute for Regenerative Medicine.
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