For cancer patients with tumors, there always a risk of the tumor spreading to a different organ, which makes fighting the cancer more difficult and risky. However, this spread of cancer very rarely occurs on skeletal muscles, which make up nearly 50% of body mass. Why don't these metastatic cancer cells move to and grow on these skeletal muscles? Researchers are still unclear. Now, with the help of a recent $1 million grant from the W.M. Keck Foundation, a research team at Fred Hutchinson Cancer Research Center will focus on studying this elusive topic. (Image courtesy of CC BY-SA 3.0 via Wikimedia Commons)Read More
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Between 3 to 20 percent of women with breast cancer will develop another primary cancer tumor in the opposite breast within ten years of the first diagnosis. Though previous studies have identified some environmental, genetic, and treatment-related risk factors for contralateral breast cancer, scientists still don’t fully understand what causes these second primary cancers.Read More
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In March, the National Cancer Institute (NCI) approved a $3.7 million, five-year grant to extend Dr. Eric Chow’s research into improving treatment of cardiovascular risk factors in childhood cancer survivors. Dr. Chow is a clinical researcher, epidemiologist, and pediatric oncologist at Fred Hutchinson Cancer Research Center in Seattle, Washington. This is one of two research grants to be awarded to Dr. Chow by the National Cancer Institute. The NCI also chose to extend Dr. Chow’s study of the long-term efficacy of a medication meant to minimize or prevent heart injury in pediatric patients going through chemotherapy. This $2.7 million in research funding will allow for four more years of studies regarding the use of dexrazoxane in pediatric cancer patients.Read More
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DefeatHIV, an initiative based out of the Fred Hutchinson Cancer Research Center in Seattle, WA, has been researching potential cures for HIV over the past 5 years. Their research has focused on the use of blood cells genetically modified to be resistant to the HIV virus. It was recently announced that the National Institutes of Health (NIH) awarded the DefeatHIV team a new grant of $23.5 million that will continue to support their research on this potential cure for an additional 5 years.Read More
Small-cell lung cancer (SCLC) makes up about 10 - 15% of all lung cancer diagnoses, and is caused by smoking and inhaling second-hand smoke. This is an aggressive type of cancer that spreads quickly, and recurs extremely frequently after patients undergo chemotherapy treatments. Treatments for SCLC have not changed much in the past 30 years, but a team of researchers led by the Fred Hutchinson Cancer Research Center in Seattle has been investigating potential new therapy methods for the cancer and recently uncovered a gene that has the potential to be used in biology-based treatments for SCLC. (Image courtesy of Lindsay Fox via Wikimedia Commons and EcigaretteReviewed)Read More
Millions of people suffer from allergies nationwide, (up to 30% of Americans, according to the Center for Disease Control), but for most, a healthy immune system and a course of antihistamines is all that is needed for a little relief.
For others, however, diseases that complicate and degrade the immune system make every microbe and bacteria a potentially fatal nightmare. In recent years, people suffering from immune deficiencies have found some home in stem-cell transplants and other therapies, but their hope is tempered by inherent toxicities and associated side effects.Read More
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Brain surgery is an extremely delicate matter, and complicated even further when performed on children with brain cancer. These cancer cells are difficult to discern from healthy cells during brain surgery and afterward may or may not still reside in the brain where they can continue to spread and cause damage.Read More
Pancreatic cancer is one of the most rapidly spreading cancers known to man, which translates to seriously staggering death rates. According to the American Cancer Society, for all stages of pancreatic cancer combined, the one-year relative survival rate is 20%, and the five-year rate is 6%, in part because more than 80% of patient tumors have spread beyond the pancreas by the time of diagnosis. In most cases, the cancer has already spread to the point where surgical removal is impossible. (Image: Test Molecule; Los Angeles Mission College)Read More
Researchers at Fred Hutchinson Cancer Research Center have discovered that high blood concentrations of omega-3 fatty acids increase risk of prostate cancers. The latest investigations indicate that high concentrations of EPA, DPA, and DHA, which are metabolically related to fatty acids and derived from fatty fish and fish-oil supplements, are associated with a 71% increased risk of high-grade prostate cancer and an overall 43% increase in risk for all prostate cancers.
Fred Hutchinson Cancer Research Center recently received an $11 million life science research grant from the National Institutes of Health to fund the HIV Vaccine Trials Network. The organization within the NIH providing this latest round of life science funding is the National Institute of Allergy and Infectious Diseases. Project leader Dr. Margaret Juliana McElrath is a professor of medicine at the University of Washington. Her research lab studies are focused on identifying and characterizing cellular immune responses that may help protect patients against HIV infection or disease.