Dr. Jay F. Sarthy of the Fred Hutchinson Cancer Research Center has been awarded a $231,000 grant over the next four years from The Damon Runyon Cancer Research Foundation as one of five scientists receiving the Damon Runyon-Sohn Pediatric Cancer Fellowship Award. The award will be used to study pediatric brain cancer with the ultimate goal being the development of new drugs to restore the ability of cells to package DNA correctly eliminating cancer. Under the mentorship of Dr. Steven Henikoff, a geneticist, and Dr. Jim Olson, a neuro-oncologist, Sarthy will try to develop new affordable methods of studying epigenetics and DNA packaging in pediatric cancer.
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Between 3 to 20 percent of women with breast cancer will develop another primary cancer tumor in the opposite breast within ten years of the first diagnosis. Though previous studies have identified some environmental, genetic, and treatment-related risk factors for contralateral breast cancer, scientists still don’t fully understand what causes these second primary cancers.
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In March, the National Cancer Institute (NCI) approved a $3.7 million, five-year grant to extend Dr. Eric Chow’s research into improving treatment of cardiovascular risk factors in childhood cancer survivors. Dr. Chow is a clinical researcher, epidemiologist, and pediatric oncologist at Fred Hutchinson Cancer Research Center in Seattle, Washington. This is one of two research grants to be awarded to Dr. Chow by the National Cancer Institute. The NCI also chose to extend Dr. Chow’s study of the long-term efficacy of a medication meant to minimize or prevent heart injury in pediatric patients going through chemotherapy. This $2.7 million in research funding will allow for four more years of studies regarding the use of dexrazoxane in pediatric cancer patients.
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Fred Hutchinson Cancer Research Center raised over $13 million in donations at its recent Hutch Holiday Gala, the center's largest annual fundraiser held in Seattle each year. Money from the event will be used to recruit world-class researchers in pediatric oncology and to expand research infrastructure geared specifically toward pediatric cancer research.
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Small-cell lung cancer (SCLC) makes up about 10 - 15% of all lung cancer diagnoses, and is caused by smoking and inhaling second-hand smoke. This is an aggressive type of cancer that spreads quickly, and recurs extremely frequently after patients undergo chemotherapy treatments. Treatments for SCLC have not changed much in the past 30 years, but a team of researchers led by the Fred Hutchinson Cancer Research Center in Seattle has been investigating potential new therapy methods for the cancer and recently uncovered a gene that has the potential to be used in biology-based treatments for SCLC. (Image courtesy of Lindsay Fox via Wikimedia Commons and EcigaretteReviewed)
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Millions of people suffer from allergies nationwide, (up to 30% of Americans, according to the Center for Disease Control), but for most, a healthy immune system and a course of antihistamines is all that is needed for a little relief.
For others, however, diseases that complicate and degrade the immune system make every microbe and bacteria a potentially fatal nightmare. In recent years, people suffering from immune deficiencies have found some home in stem-cell transplants and other therapies, but their hope is tempered by inherent toxicities and associated side effects.
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