Tags: 2014, Harvard University, 2013, Northeast, breast cancer, breast cancer research, Massachusetts, Boston, BioResearch Product Faire Event, MA, Harvard, research news
One of the current trends in life science research is to find the microbes behind the processes and phenomenon with which we’re already familiar. Once we understand the role that bacteria play, we can replicate, enhance, or halt their methods as we need to. Such is the case at the Washington University at St. Louis, where bioresearchers are better understanding the microbes in our intestines in order to take a stab at obesity.
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Iron is the most common chemical element found on earth, and it plays a key role in the biochemical processes of almost all organisms. Though iron is an important building block of life, it is also attributed to causing cellular damage when it is released into its free catalytic form. Researchers at the University of Alabama at Birmingham recently published a report in the Journal of Clinical Investigation which sought to help understand the relationship between the protein ferritin and kidney damage caused by this free iron. This study set a foundation for future research into potential treatments to prevent acute kidney injury.
Tags: 2014, 2013, Alabama, University of Alabama, Southern, BioResearch Product Faire Event, UAlab, Birmingham, University of Alabama at Birmingham
Researchers at the University of Pittsburgh have developed a way to mimic the biological responses of animals such as octopi or cuttlefish, which change their shape in the face of danger, by eliciting a biomimetic response using hydrogels. Hydrogels are used in most contact lenses and microfluidic or fluid-controlled technologies already, but the University of Pittsburgh researchers were able to redesign them to be reconfigured and controlled by light in a self-sustained movement. The study was recently published in the journal Advanced Functional Materials.
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A new study at the University of Pennsylvania, published in the journal PLOS ONE, has had researchers develop a variant of the mu opioid receptor that is water-soluble and can be grown in large quantities in bacteria. When the mu opiod receptor binds with opioid molecules, a strong reduction in the sensation of pain occurs. Unfortunately, fatal side effects can occur. According to a University of Pennsylvania news article, researchers at the university sought to address this issue by identifying the hydrophobic amino acids on the exterior of a structured model of the protein.
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“Lombardi's mission is to prevent, treat and cure cancers, through cutting-edge research, expert and compassionate patient care, education of future cancer specialists, and service to the community,” says the Georgetown University Lombardi Comprehensive Cancer Center funding application and project abstract listed on NIH RePORTER. The Lombardi Comprehensive Cancer Center was recently awarded $1.4 million this year. “Lombardi is the only NCI-designated cancer center in the nation's capital and in the Washington metropolitan area. The District of Columbia has among the highest cancer mortality rates in the country. Thus, there is a clear need for an NCI-designated comprehensive cancer center that can bring a targeted, evidence-based strategy to cancer care and prevention to help improve the health of the community's residents.”
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Researchers at Stony Brook University in collaboration with colleagues at Johns Hopkins School of Medicine used DNA sequencing methods to make a new discovery: the direct causation of exposure to aristolochic acid (AA), which is found in a plant that’s been used in herbal remedies for thousands of years, in the development of urothelial cancer.
Tags: 2014, 2013, Northeast, cancer research, DNA Sequencing, New York, Stony Brook University, BioResearch Product Faire Event, NY, Stony Brook, research news, SunySB
When we jump into the swimming pool for some last-minute summer revelry, the worst part of getting out is the feeling of residual chlorine on our bodies. The environment doesn’t respond well to chlorine either- several synthetic chlorine-based compounds are toxic when released into nature and have taken part in the development of numerous superfund sites. Fortunately, a team from the University of Minnesota’s BioTechnology Institute is working on a way to clean up this chlorine, with help from some hungry bacteria.
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Researchers at the University of Alabama at Birmingham, led by Donald Buchsbaum, PhD, received a $2.2 million grant from the NIH this year to study pancreatic cancer. According to the University of Alabama website, Dr. Buchsbaum is quoted as saying of his research goals: "My interests are focused on the use of monoclonal antibodies that bind to the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptors for cancer therapy in combination with chemotherapy agents and radiation.” Dr. Buchsbaum and his research team began receiving funding for their studies of pancreatic cancer six years ago, though funding was limited at that time. The NIH RePORTER sheds light on the project that has received $2.2 million from the NIH this year in the proposal’s abstract:
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Researchers at Columbia University Medical Center recently conducted a study examining brains of a number of different ages donated by people who died without signs of neurologic disease. During the course of the investigation, researchers came to the conclusion that a certain hippocampus gene’s function deteriorates in older people. The researchers believe that age-related memory loss is distinct condition from Alzheimer’s or pre-Alzheimer’s, and that the condition may be treatable in the future.
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