Science researchers at Rockefeller University, Duke University and the University of California, San Francisco recently conducted a study that found that the pain and red skin associated with sunburn is caused by a molecule that’s heavily concentrated in the skin’s epidermis. The study was published in the Proceedings of the National Academy of Sciences. The results of this study could lead to a way to prevent sunburn and possibly other sources of pain.
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Tags: 2014, Rockefeller University, 2013, Northeast, sunburn, New York, RockU, BioResearch Product Faire Event, NY, recent research, recent study
Researchers at Rockefeller University, led by Brian Chait, have been awarded a $2.3 million grant by the NIH for the National Resource for the Mass Spectrometric Analysis of Biological Macromolecules. According to the Rockefeller University website, the National Resource for the Mass Spectrometric Analysis of Biological Macromolecules is now in its 39th year of receiving funding from the NIH. The abstract on the NIH RePORTER says of the project:
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Tags: 2014, Rockefeller University, 2013, Northeast, New York, RockU, BioResearch Product Faire Event, NY, NIH funding, NIH grant, NIH award
Science researcher C. David Allis is head of the Laboratory of Chromatin Biology and Epigenetics at Rockefeller University, and he has been awarded a $1 million grant from the Starr Cancer Consortium. As the leader of one of five cancer research teams from New York City based members of the consortium, Allis was one of 27 people to submit a grant application and a member of one of five collaborative cancer research teams selected as a winner. The Starr Cancer Consortium gave out a total of $5 million dollars over two years.
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Tags: 2014, Rockefeller University, 2013, Northeast, New York, RockU, BioResearch Product Faire Event, NY, cancer research funding, cancer research grant
Memorial Sloan-Kettering Cancer Center cell engineering researchers and their clinician colleagues have been in the news recently for a successful experimental cell therapy. Called targeted immunotherapy, a patient's T cells are genetically altered in the lab, then reintroduced with the directive to target and kill cancer cells. The treatment was carried out on a group of adults who all suffered from a rapidly progressing form of leukemia that had not responded to chemotherapy. All five went into remission after the novel cell treatment, and three have stayed that way for a number of months. Results of the ongoing clinical trial appeared in the March 20 online edition of the journal Science Translational Medicine, along with an article in the New York Times.
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Tags: 2014, Rockefeller University, 2013, Northeast, Leukemia, immunotherapy, cancer research, New York, Memorial Sloan-Kettering Cancer Center, Cancer Treatment, Immune System, Cell Research, RockU, BioResearch Product Faire Event, NY, New York City, MSKCC
Of the eleven scientists just announced as winners of the new Life Sciences Breakthrough Prize, four of them have their labs within a block or two of each other in Manhattan: two at Rockefeller University, one at Weill Cornell Medical College, and one at Memorial Sloan-Kettering Cancer Center. The prize, given to recognize past achievement in research aimed at curing disease and extending human life, comes with $3M to allow each of those researchers the freedom and flexibility to pursue even more groundbreaking work in the future. The founding sponsors of the prize are tech entrepreneurs Sergey Brin (Google) and Anne Wojcicki, Mark Zuckerberg (Facebook) and Priscilla Chan, Art Levinson (Apple), and Yuri Milner (venture capitalist). The 11 winners this year will serve on the board to choose 5 winners each in subsequent years.
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Tags: 2014, Rockefeller University, 2013, Northeast, cancer research, women in science, New York, Weill Cornell, Memorial Sloan-Kettering Cancer Center, RockU, BioResearch Product Faire Event, NY, New York City, Cancer Center, Rockefeller
Researchers in the St. Giles Laboratory of Human Genetics of Infectious Diseases at Rockefeller University have recently published the results of a study that demonstrates how organs like the brain have their own defense systems which, when disrupted, can permit disease despite a healthy white blood cell count. The key is the production of interferon, which are proteins triggered by a receptor called TLR3 that send up the alarm to fight infection (by interfering with the pathogen's reproduction). When that TLR3 receptor is faulty on a neuron or other brain cell, no interferon is produced and the patient can suffer a disease of the brain even though that same pathogen is being combatted effectively in other parts of the body. We now know there seem to be localized systems of immune response within specific organs, and that interferon therapy may help patients with rare localized diseases.
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Tags: Rockefeller University, biomedical research, Stem cell research, New York, 2012, Immune System, brain research, BioResearch Product Faire Event, NY, New York City
Though the general consensus seems to be that the Northeast weathered deadly storm Sandy relatively well thanks to warnings and emergency plans put into action, there were unexpected casualties beyond the loss of over 80 human lives. Massive flooding in the lower New York Metro Area was not on the radar to the extent that it actually transpired, and basements that were thought to be flood-safe turned out not to be. That was the case at New York University's Smilow Research Center, where animal labs underground were inundated and approximately 10,000 research mice and rats drowned and lab equipment was ruined. On the upper floors, precious biological samples and reagents were lost as freezers and refrigerators shut down. Other research institutions in the area fared better.
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Tags: Mount Sinai School of Medicine, Rockefeller University, Northeast, animal research, research mice, University of Texas, New York, 2012, Stony Brook University, Austin, Philadelphia, MSSM, BioResearch Product Faire Event, NY, Front Line event, science research, research laboratories, New York City, Research equipment, Stoneybrook
It's an honor to receive a postdoctoral fellowship to continue your professional training in an established lab just after getting your PhD; it's even more prestigious to to win a postdoc fellowship to start your own lab research program. Dr. Brad Rosenberg finished the clinical portion of his M.D.-PhD program last year at Weill Cornell Medical Center, having earned his PhD from Rockefeller University through the Tri-Institutional Program two years earlier. This year he is conducting his own research at Rockefeller using advanced high-throughput sequencing techniques to analyze lymphocytes in the immune system.
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Tags: Rockefeller University, New York, 2012, Immune System, BioResearch Product Faire Event, Funding, NY, NIH, New York City, BRPF
"High-risk, high-reward" life science research funding isn't something we hear about very often in these days of fiscal belt-tightening, especially coming from the private sector. Fortunately the NIH is still committed to supporting exceptional life science labs that take the road less travelled, with the Director's Transformative Research Awards and the Director's New Innovator Awards, because the potential payoff justifies the gamble taken. The NIH has standard criteria by which they evaluate grant proposals. Realizing that those criteria would enevitably leave out some of the most daring and ground-breaking research, they came up with the High Risk awards. 2012 Director's Awards from the NIH Common Fund (totalling some $155M) have gone to 81 investigators, and 5 of them are faculty members and heads of laboratories at Rockefeller University.
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Tags: Rockefeller University, Northeast, RNA research, New York, 2012, biology research, BioResearch Product Faire Event, Funding, NY, NIH, New York City, new research grants, Rockefeller, early career funding
The Clinical & Translational Science Center (CTSC) headquartered at Manhattan's Weill Cornell Medical College has just received a $49.6M renewal of its 5-year grant by the NIH's National Center for Advancing Translational Sciences (NCATS) in order to continue its work. Launched seven years ago, the the CTSC set out to realize the successful integration of inter-institutional resources among neighbors on York Avenue and the immediate area. The resulting cluster of New York's East Side institutions forms a unique and cohesive biomedical complex collectively dedicated to accelerating the clinical application of basic science discoveries.
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Tags: Rockefeller University, Northeast, Translational Research, New research facilities, new science wet labs, New York, Columbia University, 2012, Weill Cornell, Columbia, MSSM, RockU, BioResearch Product Faire Event, Funding, NY, NIH, Stoneybrook, SunySB, NYC campus competition, Mt Sinai School of Medicine