Science researchers at Rockefeller University, Duke University and the University of California, San Francisco recently conducted a study that found that the pain and red skin associated with sunburn is caused by a molecule that’s heavily concentrated in the skin’s epidermis. The study was published in the Proceedings of the National Academy of Sciences. The results of this study could lead to a way to prevent sunburn and possibly other sources of pain.
“We see the effects of harmful sun rays to our body surface and we feel the pain associated. We now have a glimpse into how our epidermis instructs our brain to feel the pain,” said Elaine Fuchs, Rebecca C. Lancefield Professor at Rockefeller University and a Howard Hughes Medical Institute investigator.
According to an article published on the Rockefeller University website, part of the study involved researchers trying to block the pain pathway using a pharmaceutical compound called GSK205. When applied to the mice, the researchers found that the animals did not experience the pain-causing and skin-disrupting effects of sunburn. By blocking certain channels in the epidermis, the skin can’t communicate with sensory neurons. This may not prevent skin damage, it does lessen pain.
“Our understanding of how mammals respond to harmful UVB rays is altered, both at the molecular as well as the cellular level,” says Dr. Liedtke, associate professor of neurology and a physician at Duke University Medical Center. “At the molecular level, TRPV4 is a key element of the UVB-sensing machinery in skin. At the cellular level, skin keratinocytes can sensitize the entire organism to feel the pathological pain of sunburn, which means a temporary re-programming of the pain-conducting organization of the central nervous system has been implemented as a result of TRPV4-signaling by skin keratinocytes.”
A woman's sunburned back
Image courtesy of Kelly Sue DeConnick and Wikimedia Commons
Rockefeller University works with other powerhouse research institutions to conduct groundbreaking studies every year. Lab suppliers working to sell lab equipment at Rockefeller University life science marketing events will find that the school has a great deal of research funding available for researchers interested in purchasing lab products. In 2012, the NIH awarded Rockefeller University $70.1 million in research funding. In addition to the NIH awarding a great deal of funding, the NSF also gave Rockefeller University $844,385 in 2012.
Given these funding statistics, lab suppliers marketing lab products and working to sell lab equipment may want to take advantage of the market available at Rockefeller University. Biotechnology Calendar, Inc. invites all lab suppliers to network with researchers, lab managers and purchasing agents by exhibiting at our Rockefeller BioResearch Product Faire™ Event on October 2nd, 2013. Last year, our Rockefeller BioResearch Product Faire™ Event attracted 398 attendees. Of those attending, 102 were purchasing agents, professors and post docs, and 22 were lab managers. The attendees came from 28 different research buildings and 77 departments across campus.
Biotechnology Calendar, Inc. is a full-service science research marketing and events-planning company that organizes life science marketing events at top research universities across the country. If you’d like to sell lab equipment and market your lab products at other life science marketing events closer to home, we encourage you to view our 2013 calendar of events. For more information on our Rockefeller BioResearch Product Faire™ Event, or to view more funding statistics for Rockefeller University, click on the button below.
