Patrick Moore, M.D., M.P.H., director of the Molecular Virology Program at the University of Pittsburgh Cancer Institute (UPCI), will receive more than a $2 million new grant from the NIH to continue research into the human cancer virus that causes most Merkel cell carcinomas, a rare but deadly skin cancer. This new grant will fund the research through March 2019.
Science Market Update
Researchers at the University of Pittsburgh recently received $10.4 million in life science funding from the NIH at the end of July this year. The administering center for the award at the NIH was the National Center for Advancing Translational Sciences, and the life science funding will be given to the University of Pittsburgh Clinical and Translational Science Institute. More information on the Clinical and Translational Science Institute is available on the NIH RePORTER project abstract:
Researchers at the University of Pittsburgh have made a groundbreaking contribution to life science research: Researchers helped a mouse heart to beat again after its own cells were replaced with human heart precursor cells, marking the first time this has ever been done. According to a University of Pittsburgh news article, the researchers say it may soon be possible to take a skin biopsy from a human patient to regenerate an organ able to be transplanted.
Reading our Science Market Update blog is a great way to stay informed of industry trends and research, funding and life science building news, but did you know that there is also a great deal of funding and life science market news available on our company news blog? We have put together a list, including links to the articles, of some recent news posted on our Life Science Company and Industry News Briefs blog available to life science sales and marketing professionals interested in staying informed of life science marketing and industry news.
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Researchers at the University of Pittsburgh have developed a way to mimic the biological responses of animals such as octopi or cuttlefish, which change their shape in the face of danger, by eliciting a biomimetic response using hydrogels. Hydrogels are used in most contact lenses and microfluidic or fluid-controlled technologies already, but the University of Pittsburgh researchers were able to redesign them to be reconfigured and controlled by light in a self-sustained movement. The study was recently published in the journal Advanced Functional Materials.
Science researchers at the University of Pittsburgh recently published a study that found that patients suffering from SAD – Seasonal Affective Disorder – had misconceptions about sleep similar to those of insomniacs that prevent them from sleeping soundly at night. According to a University of Pittsburgh news article, the paper was titled “The Role of Beliefs and Attitudes About Sleep in Seasonal and Nonseasonal Mood Disorder, and Nondepressed Controls” and was published in the Journal of Affective Disorders this May.
Lab scientists at the University of Pittsburgh Cancer Institute and UP's Center for Biologic Imaging have recently published an important paper in the Journal of Cell Science that sheds light on a novel method of interrupting mitosis in a cell by effectively depriving its mitochondria of a key protein. The resulting replication stress means cancer cells are stopped from successfully multiplying. Colorful images of the targeted cells actually show them stuck in anaphase trying to divide and subsequently tearing themselves apart. By identifying a compound that carries out this protein interference and disrupts normal mitochondrial fission, researchers have identified a promising therapeutic avenue for halting cancer growth.
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In order for HIV to proliferate and infect new cells in the body, a number of proteins need to interact with each other in just the right way. If they don't, the virus is not able to multiply and spread, and HIV infection cannot develop into full-blown Auto Immune Deficiency Syndrome (AIDS). It's a case of finding a weak link and exploiting its potential to disrupt an entire supply chain. In the University of Pittsburgh microbiology lab of Dr. Thomas Smithgall, this protein sabotage approach has successfully allowed them to identify a helper molecule that, if compromised, could form the basis of an effective new HIV/AIDS treatment therapy. The paper documenting their research appeared in the January 24 issue of Chemistry & Biology.
The 225th Anniversary of the University of Pittsburgh will be celebrated this year. One of their most notable accomplishments was contributing to the launch of the "Biotech Industry". Herbert Boyer, a Pitt PhD graduate helped discover how to cut and transfer individual genes within the DNA molecule and transfer them from one organism to another. Boyer eventually founded Genetech, widely considered one of the first successful biotech companies.
With many accomplishments, in 2000, Herbert Boyer and his wife established the Herbert W. and Grace Boyer Chair in molecular biology in the University of Pittsburgh’s Department of Biological Sciences. Today the Herbert W. and Grace Boyer Chair in Molecular Biology is used to support an outstanding faculty member in the field of post-genomic molecular biology.
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