After receiving $2 million in philanthropic gifts in honor of Thomas Hartman, the Thomas Hartman Center for Parkinson’s Research in the Stony Brook University Department of Neurobiology and Behavior was dedicated in a ceremony on June 13th, 2013. Thomas Hartman was a much loved priest, television and radio personality, and believer in many causes who was diagnosed with Parkinson’s disease in 2004.
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Researchers at Columbia University recently conducted a study aiming to identify an Alzheimer’s gene in African-Americans. The results were published in the April 10 issue of the Journal of the American Medical Association, and the study was funded by NIH research grants. African-Americans with the ABCA7 gene have almost twice the amount of risk of developing late-onset Alzheimer’s disease. According to a Columbia University news article, the gene is involved in producing cholesterol and lipids, and researchers believe that lipid metabolism may be a key pathway in Alzheimer’s disease in African-Americans, more so than it may be in white people.
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Lab suppliers marketing university lab equipment and hoping to increase scientific product sales may want to take a closer look at Stony Brook University’s latest research funding grants. Stony Brook University was recently awarded $2.45 million from the New York state government to fund programs are that have been designated as having “high need.” The government will be awarding $12 million to 36 SUNY colleges over the next three years.
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If significant research is any indication of the quality of lab sales leads at life science marketing events held on Columbia University’s campus, this next story is worth reading about. Columbia University Medical Center researchers conducted a significant study that has identified a number of metabolic expression changes in the gene expression data from 22 tumor types. The analysis also points to hundreds of medications that could remove a tumor’s fuel supply or inhibit a tumor’s synthesis. The study was published in Nature Biotechnology.
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A $20 million gift from Philip and Cheryl Milstein to the Columbia University Medical Center was announced recently. The donation will be used as part of an effort to rejuvenate the medical campus with construction of the Medical & Graduate Education Building on Haven Street between West 171st and West 172nd Streets. Administrators at Columbia University Medical Center said the building will include “innovative classroom and study spaces that will incorporate state-of-the-art information technology while facilitating collaborative, team-based learning.” The new building’s function will be the training of students in the College of Physicians and Surgeons and the biomedical science departments in the Graduate School of Arts and Sciences. (Read our earlier blog on this new construction project at CUMC here.)
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Memorial Sloan-Kettering Cancer Center cell engineering researchers and their clinician colleagues have been in the news recently for a successful experimental cell therapy. Called targeted immunotherapy, a patient's T cells are genetically altered in the lab, then reintroduced with the directive to target and kill cancer cells. The treatment was carried out on a group of adults who all suffered from a rapidly progressing form of leukemia that had not responded to chemotherapy. All five went into remission after the novel cell treatment, and three have stayed that way for a number of months. Results of the ongoing clinical trial appeared in the March 20 online edition of the journal Science Translational Medicine, along with an article in the New York Times.
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Dr. Thomas Jessell is a developmental neurobiologist at Columbia University Medical Center and the latest recipient of the Scolnick Prize in Neuroscience, which includes a $100,000 award. In the Jessell Lab in the Hammer Health Sciences Building, researchers study the vertebrate central nervous system to understand how neurons become encoded at the embryonic level, particularly in the spinal cord. The Scolnick Prize singles out Jessell's work for identifying signaling molecules and transcriptional code that establish a linkage between functional circuitry and motor behavior. Also a member of Columbia's Motor Neuron Center, which is dedicated to the study of motor neuron diseases like ALS, Dr. Jessell is a faculty member in the Department of Biochemistry and Molecular Biophysics, a Howard Hughes Medical Institute investigator, and part of the larger Columbia Neuroscience interdisciplinary research community. He will travel to Boston in April to accept the prize and deliver a lecture (see image at right). The Scolnick Prize is given out by the McGovern Institute for Brain Research at MIT. According to McGovern chairman Robert Desimone, from a recent CUMC press release:
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Of the eleven scientists just announced as winners of the new Life Sciences Breakthrough Prize, four of them have their labs within a block or two of each other in Manhattan: two at Rockefeller University, one at Weill Cornell Medical College, and one at Memorial Sloan-Kettering Cancer Center. The prize, given to recognize past achievement in research aimed at curing disease and extending human life, comes with $3M to allow each of those researchers the freedom and flexibility to pursue even more groundbreaking work in the future. The founding sponsors of the prize are tech entrepreneurs Sergey Brin (Google) and Anne Wojcicki, Mark Zuckerberg (Facebook) and Priscilla Chan, Art Levinson (Apple), and Yuri Milner (venture capitalist). The 11 winners this year will serve on the board to choose 5 winners each in subsequent years.
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The Brain Activity Map project could be the next big federal life science research endeavor, with no less a goal than the mapping of the entire living brain and all its neuronal activity. Like the Human Genome Project of the 90's, the not insignificant financial outlay is being presented as an investment that will net even bigger returns, both in terms of new technology and a vastly increased understanding of the mind. President Obama is expected to include the multi-billion dollar, decade-long funding in his upcoming budget proposal, and neuroscience research was a topic he addressed specifically in his recent State of the Union address.
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