In the information age, cancer research is shifting from data generation to bioinformatics. This interdisciplinary field develops methods and software tools for understanding biological data. Bioinformatics combines computer science, statistics, mathematics, and engineering to analyze and interpret biological data. The Cancer Prevention & Research Institute of Texas (CPRIT) recently awarded W. Jim Zheng, Ph.D., of The University of Texas Health Science Center at Houston (UTHealth) a five-year, $5.8 million grant to sort through information that could lead to cures for cancer.
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The National Cancer Institute awards the University of Illinois at Urbana-Champaign roughly $5 million in research funding each year. This funding supports a number of cancer research projects conducted at the university. One such project is a ground breaking study of nanoparticles that researchers designed to specifically bind to a protein that marks the surface of breast cancer stem cells and destroy them. These elusive and rare cells can cause cancer to come back years after the tumor has been treated.
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Researchers at Texas Medical Center’s (TCM) Houston Methodist Hospital have invented a way to overcome chemotherapy drug resistance and destroy the deadliest type of brain tumors without destroying the surrounding tissue. This targeted approach combines a “smart drug” with chemotherapy. In animal models of human brain cancer, this smart drug prolonged life by over six fold.
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The $10 million gift from Andrew M. and Jane M. Bursky will advance cutting-edge research at the newly named Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs. Research at the center focuses on harnessing the immune system to fight cancer, infectious diseases, and autoimmune disorders.
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According to the American Cancer Society, 1 in 8 American women will develop invasive breast cancer in their lifetime, and each year over 40,000 women die from it. However, thanks to research conducted at the University of Illinois Urbana-Champaign, the number of deaths due to breast cancer may soon be significantly reduced.
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Antibodies are essential for keeping the body healthy, as they are produced in the immune system and sent to fight harmful substances. Since they are essential for fighting off unwanted antigens in the body, antibodies are a hot topic that researchers are constantly studying. Recently, a research team from Duke University developed an antibody that specifically targets cancer cells, providing a possible new immunotherapy for cancer. (Image of antibody-antigen complex courtesy of Alejandro Porto via Wikimedia Commons)
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Researchers around the world are constantly studying ways to create new treatment methods to fight cancer. With so many different forms of cancer, using one treatment method is not always effective for everyone battling this disease. Recently, a team of scientists in Chicago teamed up to create a new treatment method. Researchers from the University of Chicago and the biotechnology company Evelo Biosciences have partnered to develop a new microbiome-based immunotherapy treatment method for fighting cancer.
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Acute myeloid leukemia (AML) is the most common form of leukemia affecting the blood and bone marrow, and has been responsible for 1.8% of cancer deaths in 2016. Because it is so prevalent, many research teams around the world study this disease in search of new treatment methods. One of these research teams, from Harvard University, has joined up with the pharmaceutical company Merck in a $20 million collaboration to develop new therapeutics for leukemia.
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