Two prominent researchers at UC Davis are under a microscope for their work in stem-cell biotechnology. The pair from University of California, Davis was awarded close to $4 million in funding to improve biotechnology intended for physicians studying stem cell treatments.
The two grant awards, of over $1.8 million each, were awarded to Laura Marcu and Kent Leach by the California Institute for Regenerative Medicine (CIRM) to continue developing technology that is used in stem cell treatments for vascular disease, bone and cartilage repair.
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By combining time-lapse luminescence microscopy with a microfluidic device, researchers at Duke University were able to track the dynamics of cell cycle genes in single yeast with subminute exposure times over many generations. Typically time-lapse fluorescence microscopy of genetically encoded fluorescent proteins is the gold standard for measuring in vivo dynamics of gene expression in single cells.
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DNA is a lot like a genetic recipe: change up the order of the ingredients, and you might get an entirely different dish. At the University of Michigan, Ann Arbor, bioresearchers are cooking up some new results that better explain the effects of modifying DNA and what that means for evolution as a whole.
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Movies like "Happy Feet" and "March of the Penguins" often remind us of how cute penguins are in the cold, Antarctic conditions where they live. These movies, however, fail to mention another species of penguin that reside in warmer climates and is slowly dying out: African penguins. Although they are on track to be extinct within the next 20 years, the Pueblo Zoo in Colorado and Colorado State University, Fort Collins recently performed cancer treatments on the oldest living African penguin in the world, ensuring that the penguin will be healthy enough to live a longer life. (Image of African penguin (not Tess) courtesy of Wikimedia Commons).
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Polycystic Kidney Disease (PKD) is considered to be one of the most fatal genetic diseases that affects more then 500,000 people in the United States. This disease, caused by a mutation in certain genes, causes the growth of cysts on the kidneys, which lead to kidney enlargement and failure. The are currently no treatments to permanently cure or halt the progression of this disease. Current solutions for PKD are receiving either a kidney transplant or staying on dialysis for the rest of ones life, neither of which are ideal situations.
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Already the nation’s leading university for medical research, UCSF continues to expand thanks to a generous and recent donation.
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Researchers from the Perelman School of Medicine at the University of Pennsylvania and the Novartis Institutes for BioMedical Research have discovered a potential new method for treating brain cancer using specially engineered immune cells.
According to a university press release, personalized immune cells were engineered by UPenn scientists in order to seek out and attack a type of deadly brain cancer, and were found to be both safe and effective at controlling tumor growth in mice that were treated with these modified cells.
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A team of researchers at The University of Cincinnati has found new proteins that help maintain gene stability. Their work is especially relevant to diseases that are caused by genetic instability, like cancer.
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With the assistance of a 5-year, $10.7 million grant from the National Institute of Allergy and Infectious Disease (NIAID), researchers from the University of Maryland School of Dentistry and the University of Maryland School of Medicine will work together to study the causes, prevention, and treatment methods for 2 commons STD's: Chlamydia and Gonorrhea. This grant renews a previous 5-year, $12 million grant Baltimore researchers received to study STDs. (Image courtesy of Acroterion, via Wikimedia Commons).
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While not necessarily always the best course of treatment, the majority of men with prostate cancer will go with radiation treatment when confronted with options for treating the potentially deadly disease. Unlike other options, including surgery and chemotherapy, radiation treatment is a relatively “outpatient” procedure - with no anesthetic needed, targeted effectiveness, and relatively few short term side effects.
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