Researchers at Columbia University recently conducted a study aiming to identify an Alzheimer’s gene in African-Americans. The results were published in the April 10 issue of the Journal of the American Medical Association, and the study was funded by NIH research grants. African-Americans with the ABCA7 gene have almost twice the amount of risk of developing late-onset Alzheimer’s disease. According to a Columbia University news article, the gene is involved in producing cholesterol and lipids, and researchers believe that lipid metabolism may be a key pathway in Alzheimer’s disease in African-Americans, more so than it may be in white people.
Tags: 2014, 2013, Northeast, New York, Columbia University, Columbia, BioResearch Product Faire Event, NY, New York City
On May 2nd, 2013, a very important addition to the WSU Pullman campus was dedicated. The Veterinary and Biomedical Research Building (VMRB) is now the seventh connected building in the WSU Research and Educational Complex. This new building will foster research relating specifically to biomedical questions revolving around human and animal health.
This development has been under construction since August 2010 and is the most newly added member to the Research and Educational Complex on the WSU Pullman campus. This $96 million dollar investment by WSU will focus on many health issues including:
- Heart health: How, by uncovering the biophysical mechanisms of cardiac muscle contraction, new discoveries into cardiac function and disease can be revealed.
- Emotional health: How understanding the basis of emotions of companion and production animals can improve the lives of people with affective disorders.
- Sleep and circadian rhythms: How rhythms, dysrhythms, and circadian biology affect animal biology and can improve and inhibit daily functions in animals and people.
- Neurological diseases: How neurodegenerative diseases, such as Parkinson’s disease, can be treated more effectively by discovering the underlying causes and subsequently creating treatments to repair the loss of functionality.
- Obesity and Diabetes: How obesity and diabetes can be prevented by studying and understanding the relationship between the consumption of food and how energy is consequently regulated into the body.
- Drug addiction: How the biological actions of commonly abused drugs can be used to reverse the destrctive nature of addiction and help prevent the relapses of drug users.
This research facility is operating east of the Martin Stadium entrance and south of the Beasley Coliseum parking lot. This building boasts 77,250 net square feet (128,000 gross square feet) of state-of-the-art space, highly suitable for biomedical research, health science teaching, and research programs. Also included in this structure is a vivarium (an indoor facility for safely housing animals and plants in their natural environments for humane scientific observation), which will allow for gene targeting of the animals and provide necessary quarantined space to guarantee uncontaminated research. These labs and offices were specifically designed with the Veterinary Medicine Department of Integrative Physiology and Neuroscience in mind.
On the subject of this exciting new development, WSU regent Scott Carson remarks, “This building is the beginning. It’s our opportunity to compete for those wonderful young people that will be coming here in the future - the researchers that will do wonderful work because of the collaborative environment that this represents.”
Washington State University’s College of Veterinary Medicine (CVM) is one of the top leaders in research benefiting to animal and human health and well being. In fact, solely during the 2006 fiscal year, the research faculty placed the CVM well into the top tier of all veterinary schools by working with over $12.5 million in competitively funded research.
Some of these specialized areas are:
*Food & water-borne diseases
*Cardiovascular medicine & physiology
*Immunology and infectious diseases
*Neurobiology
*Microbial genomics and proteomics
Tags: 2014, 2013, biomedical research, Washington, WSU Pullman, WA, Northwest, WA research, WSU, Washington State University, Washington Life Science, BioResearch Product Faire Event, buiding. new building, research science information, Biomedical Research Funding, Pullman
Science researchers at the University of Pittsburgh recently published a study that found that patients suffering from SAD – Seasonal Affective Disorder – had misconceptions about sleep similar to those of insomniacs that prevent them from sleeping soundly at night. According to a University of Pittsburgh news article, the paper was titled “The Role of Beliefs and Attitudes About Sleep in Seasonal and Nonseasonal Mood Disorder, and Nondepressed Controls” and was published in the Journal of Affective Disorders this May.
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As the gardeners and farmers among us tend to their summer crops, a thriving community of gardeners is busy beneath our feet. As rushed and single-minded as ants seem to be, some of them are maintaining gardens of fungi at this very moment. Bioresearchers at the University of Wisconsin, Madison are taking note of these miniature horticulturalists and how their curious habits might aid humans in their search for sustainable energy sources.
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Science researchers at Duke University recently conducted a study that found that patients with a high genetic risk of asthma were 36% more likely to develop severe life-long asthma than those who are not genetically at risk. The researchers said, however, that the research is still in its early stages and not yet ready as a reliable clinical test.
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Science researchers at the University of Georgia, the Charlie Norwood VA Medical Center in Augusta and the Georgia Regents University have discovered a direct relationship between Alzheimer’s disease symptoms and two specific antibodies. The discovery may lead to a much-anticipated diagnostic blood test for the disease. The research team published their findings in the Journal of Gerontology: Medical Sciences and found that as two specific proteins’ concentration increases, dementia also increases.
Tags: 2014, 2013, University of Georgia, Southern, Georgia, UGA, BioResearch Product Faire Event, Athens, GA
Science researchers at Harvard University have discovered a gene found in the most devastating forms of cancer that controls embryonic stem cell self-renewal. The gene, SALL4, enables stem cells to keep dividing rather than grow into mature cells. The gene is re-expressed in almost all cases of acute myeloid leukemia and between 10 to 30 percent of lung, ovarian, gastric, liver, breast and endometrial cancer. Researchers say they can make a strong case that the gene plays a part in tumor formation. The breakthrough marks the beginning of a search for a drug that can block the gene’s activity.
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Scientists at Georgetown University conducted a study published in Human Molecular Genetics that gives insight into a groundbreaking new strategy for treating neurodegenerative diseases featuring an unusual buildup of proteins, such as Alzheimer’s disease, Parkinson’s, frontotemporal dementia, amyotrophic lateral sclerosis, Huntington disease and Lew body dementia, to name a few. According to a Georgetown University news article, the researchers found that when the drug nilotinib is used to treat chronic myelogenous leukemia, it causes cancer cells to go into autophagy, a biological process that causes the death of cancerous tumor cells.
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Physical adaptation is usually thought of as a very slow process. It might take a species of bird several generations to evolve a beak suited for eating fruit compared to, say, pecking wood. This change would involve the death of several birds with “incorrect” sets of genes and the survival of one type of bird with a “correct” set of genes. But what if a creature had a huge library of genes, so that they might bypass natural selection by simply expressing the right genes for their environment? That’s what researchers at Washington University at St. Louis have found occurs in the versatile fire salamander.
Tags: 2014, Washington University St. Louis, Midwest, 2013, Washington University, Missouri, WashU, WUSTL, BioResearch Product Faire Event, MO, St Louis