Bacterial cells commonly act as little machines in the lab of a bioresearcher. Some fluoresce as they bind to certain particles, others change color based on the presence of a certain chemical in solution. Useful as these cells are, they are generally pre-set; each lab has to find one that does the necessary job or wait for one to be discovered. Now the wait is over – thanks to a research team at the University of Michigan, Ann Arbor, where programmable bacterial cells are quickly becoming a reality.
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Occasionally in the research world, investigation in one particular study can lead to accidental and novel discoveries in another. Such was the case recently as the University of Michigan, Ann Arbor, where life science researchers working on zebrafish embryos stumbled upon a revelation about colon cancer that also applies to humans.
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The method of three-dimensional printing, which conjures up solid objects from 3D computer models, is beginning to make a larger impact on the world of life science technology. Though 3D printing was developed almost thirty years ago, its use in conjunction with biology began fairly recently but is quickly increasing. In fact, bioscientists from the University of Michigan, Ann Arbor just used 3D printing to save the life of a baby.
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It has long been known that mercury, which in high enough levels is toxic to humans, is found in several kinds of fish. But the reason fish contain mercury in the first place has always eluded us- until now. Life science researchers at the University of Michigan, Ann Arbor have found the reasons (indeed, there are multiple) and have concluded that the levels of mercury in fish are actually rising to this day.
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Despite its effectiveness and potency, chemotherapy is highly disputed because at its base level, it’s exposing the body to high amounts of radiation. In some cases, the amount of radiation needed to kill a cancerous tumor is more than the human body can take. At the University of Michigan, Ann Arbor, researchers are working to change this by making humans more resistant to chemotherapy.
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When speaking about cryptography, one likely imagines a military or computerized setting, where a group of people tries fervently to decipher the coded messages of their enemy in order to gain valuable intelligence. But the same thing is happening in labs at the University of Michigan, Ann Arbor, only with microbiologists cracking the code of cancer cells.
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In a potentially dangerous situation, many animals release stress hormones into the body to prepare the animal for raw survival. Sometimes these evoke defense mechanisms and sometimes they assist in fleeing from danger, hence the idea of a “fight or flight” response. Now, research at the University of Michigan, Ann Arbor shows that tadpoles instead choose a third option: physical transformation.
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The National Eye Institute, an NIH agency dedicated to vision research, recently announced the winners of their Challenge to Identify Audacious Goals in Vision Research and Blindness Rehabilitation, or the Audacious Goals Challenge for short. The competition was open to professionals and members of the public and called upon them to think big and bold about vision research goals for the next decades. The prize money was nominal ($3,000) but included an invitation and travel money to attend and present their ideas at the NEI Audacious Goals Development Meeting in Maryland later this month. The real prize, of course, was the opportunity to help set research and funding goals for the next 10-12 years. Of the 500 or so proposals submitted, 10 visionaries were selected as winners.
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The University of Michigan at Ann Arbor is one of the most richly funded markets in the country for biotechnology vendors and lab suppliers, as recent NIH and NSF research funding statistics show. In 2012, the NIH gave the University of Michigan $456.3 million in research funding. The money has been awarded to various departments for research projects including:
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There's been a lot of news coming out of Chicago this week from the annual meeting of the American Association for Cancer Research (AACR). Two announcements concerning prostate cancer research are especially worth broadcasting. An Ann Arbor pathologist, Arul M. Chinnaiyan, of the University of Michigan Comprehensive Cancer Center, will be leading a "dream team" of specialists from 5 of the top cancer research institutes in the world in a $10M, 3-year research project titled “Precision Therapy for Advanced Prostate Cancer.” The funding comes from AACR partner, Stand Up To Cancer (SU2C), and the Prostate Cancer Foundation (PCF). Heading up the team with Dr. Chinnaiyan is Dr. Charles L. Sawyers of Memorial Sloan-Kettering Cancer Center in New York.
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