Researchers at Texas Medical Center’s Rice University recently discovered that Huntington’s Disease might be triggered by a repeating nucleotide sequence in the gene for a mutant protein. The research team conducted this study by analyzing proteins that were suspected to misfold and form plaques in the brains of patients with neurological diseases.
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An estimated 30,000 people in the United States are afflicted with Huntington’s disease. Receiving a diagnosis of this genetic neurodegenerative disorder is unimaginably devastating. Sufferers slowly lose control of their movement and develop psychiatric problems over the course of 10-25 years, and often the disease is undetected until adulthood. Just this year, UC Davis researchers in Sacramento, California have discovered that human mesenchymal stem cells (MSCs) - cells with the ability to differentiate into bone cells, muscle cells, and other cell types - could be the key to developing an effective new therapy to treat Huntington’s. The promising findings are published in the journal Molecular Therapy.
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Tags: Lab Product show, Stem cell research, Neuroscience, UC Davis - Medical Center, Huntington's Disease
Huntington's Disease is a devastating, hereditary neurological disease that affects movement and mental activity. Currently, there are no cures for Huntington's Disease, and current treatments are only able to alleviate symptoms. This disease is heavily studied by researchers across the nation, and millions of dollars are given to Huntington's Disease research annually to work towards better understanding the onset and function of the disease to lead to potential treatments and cures.
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Scientists at UC Irvine have created a new method to quickly and accurately track the progression of Huntington’s disease. Irvine researchers studied Huntington’s proteins present in spinal fluid to determine that they held a “seeding” property, which is essential to the disease’s progression.
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Tags: CA, Bioresearch, University of California Irvine, California, 2015, disease research, Neuroscience, Research Funding, Neurology, Irvine, Southwest Region, UCI, UC Irvine, Huntington's Disease, BioResearch Product Faire™