Pancreatic cancer is one of the most rapidly spreading cancers known to man, which translates to seriously staggering death rates. According to the American Cancer Society, for all stages of pancreatic cancer combined, the one-year relative survival rate is 20%, and the five-year rate is 6%, in part because more than 80% of patient tumors have spread beyond the pancreas by the time of diagnosis. In most cases, the cancer has already spread to the point where surgical removal is impossible. (Image: Test Molecule; Los Angeles Mission College)Read More
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Researchers at Fred Hutchinson Cancer Research Center have discovered that high blood concentrations of omega-3 fatty acids increase risk of prostate cancers. The latest investigations indicate that high concentrations of EPA, DPA, and DHA, which are metabolically related to fatty acids and derived from fatty fish and fish-oil supplements, are associated with a 71% increased risk of high-grade prostate cancer and an overall 43% increase in risk for all prostate cancers.
Fred Hutchinson Cancer Research Center recently received an $11 million life science research grant from the National Institutes of Health to fund the HIV Vaccine Trials Network. The organization within the NIH providing this latest round of life science funding is the National Institute of Allergy and Infectious Diseases. Project leader Dr. Margaret Juliana McElrath is a professor of medicine at the University of Washington. Her research lab studies are focused on identifying and characterizing cellular immune responses that may help protect patients against HIV infection or disease.
Researchers at the Fred Hutchinson Cancer Research Center have recently demonstrated that lacking one copy of a gene called CTCF causes mice to develop cancer. CTCF is a DNA binding protein that exerts a major influence on the architecture of the human genome. It has been well studied but never linked to cancer.
The Fred Hutchinson Cancer Research Center received a donation of $20 million from Mike Bezos, a family member of Amazon CEO Jeff Bezos this April to support development of novel cancer immunotherapies. This donation is the largest single contribution in the Fred Hutchinson Cancer Center’s history.
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A new study by science researchers at Fred Hutchinson Cancer Research Center found that a number of lifestyle changes may be able to reduce the risk of or manage esophageal cancer. People who don’t smoke, keep their weight down, get regular exercise, eat a diet rich in fruits and vegetables, don’t eat four hours before they go to sleep, and avoid foods and beverages that give you heartburn (including caffeine, alcohol, chocolate, peppermint, onions, green peppers and foods that are high in fat) have a greatly reduced risk of getting esophageal cancer. Another Fred Hutchinson study found that cholesterol-reducing drugs are also associated with reduced risk.
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The Fred Hutchinson Cancer Research Center and the University of Washington Medicine in Seattle are pleased to announce the arrival soon of Dr. Eric Holland, a world-class brain cancer research scientist and neurosurgeon, who will head up the Human Biology Division at Hutch as well as the Alvord Brain Tumor Center at UW. The eminent MD/PhD is being lured away from Manhattan's Memorial Sloan-Kettering Cancer Center, where he directs the MSKCC brain tumor center and has his lab within the Cancer Biology and Genetics Program, where his team studies the molecular mechanisms underlying the development of central nervous system tumors. In addition to being the recipient of many prestigious awards over years, Holland brings with him over $3M a year in NIH/NCI funding. It's unclear how many of his 13 lab members will follow him across the country to take on new challenges at Hutch and UW.
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Dr. J. Lee Nelson (right) has been studying the fascinating phenomenon of microchimerism in the context of autoimmune disorders ever since she joined the Fred Hutchinson Cancer Research Center faculty in 1986. Microchimerism refers to the presence of two distinct sets of cells in one individual and is surprisingly common as a result of cell exchange between mother and child during pregnancy. The numbers of these outside cells is typically small, but Dr. Nelson's research has implicated them in various autoimmune responses, both positive and negative.
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