University of California life science researchers at the Jonsson Comprehensive Cancer Center have recently developed a novel and innovative cancer therapy approach that uses nanotechnology to fight brain cancer. This new technology uses nanotechnology structures called “nanodiamonds” to deliver chemotherapy agents directly to the cancerous areas in brain cancer patients.
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Lab suppliers interested in meeting researchers with life science funding available to stock their labs in San Diego will want to take note of the latest life science funding news at the University of California, San Diego. Researchers at the University of California, San Diego received a $6 million grant from the NIH this year. The money will go towards the San Diego Clinical and Translational Research Institute and will fund the internal medicine department and the school of medicine.
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Are you a lab supplier who is looking to increase your presence or expand your influence at the top California Universities? Take advantage of these upcoming life science trade shows that will provide you with an effective way to network with leading California researchers:
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Funded in part by grants from the California Institute for Regenerative Medicine and the NIH, researchers at the University of California, San Diego have come up with a simple, easily repeated RNA-based technique of generating human induced pluripotent stem cells (iPSCs). The study was published in the August 1st edition of Cell Stem Cell. The researchers’ method has wide-ranging applications for others searching for new cell therapies and use in other stem cell studies.
Tags: 2014, CA, University of California San Diego, 2013, Stem Cells, Stem cell research, Southwest, California, San Diego, SDVS, UCSD, Biotechnology Vendor Showcase
The University of California, San Francisco was recently ranked number two in the country for receiving biomedical research grants from the NIH, and it was also the number one ranked public school in the country for receiving these grants. According to the University of California, San Francisco news page, this funding allows UCSF researchers to undertake groundbreaking studies that aim at a better understanding of cancer, diabetes, HIV, Parkinson’s, Alzheimer’s and cardiovascular disease.
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In what is being hailed as a victory for both scientific research and patients' rights, the Supreme Court ruled unanimously yesterday that human genetic material cannot be patented. The case, Association for Molecular Pathology v. Myriad Genetics, has been working its way through the court system for a number of years now, led by plaintiffs including the ACLU, the American College of Medical Genetics, the American Society for Clinical Pathology, and numerous prominent genetic research scientists. The verdict invalidates the patents Myriad Genetics has held on breast cancer genes BRCA1 and BRCA2 since the 1990's and allows other labs besides theirs to test for mutations in those genes which, when present, strongly indicate a genetic predisposition to cancer. It also means that scientists can move forward in their genetic research without threat of being sued for copyright infringement. While the case was brought against Myriad specifically, the decision to disallow human gene patenting has profound implications for both scientific discovery and individual rights of ownership over our own genetic material.
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One of the reasons cancer is so successful and difficult to treat is that it uses the body's own systems to proliferate, thrive, and hide from attack. Bioresearch scientists out to target cancer are taking a similar approach, building tiny bio-vehicles for locating tumors that reach their destination without setting off a massive immune system alarm or flooding the whole body with toxic chemicals. A team of biochemists at the University of California San Diego led by Dr. Nathan Gianneschi has developed a nanoparticle that assumes a benign shape to travel covertly through the blood system, then, recognizing a tumor, reassembles via an enzymatic cue into a net to attach itself to the cancerous target.
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Researchers at the Broad Center of Regeneration Medicine and Stem Cell Research on the Parnassus Campus of the University of California San Francisco have just published the results of two related studies involving differentiated brain cells transplanted into mice. In one case, the cells were human brain cells integrated successfully into a mouse brain; in the other, epileptic mice were cured with specialized mouse brain cells. In both studies the differentiated cells were a type of interneuron progenitor called medial ganglionic eminence (MGE) cells. Unlike other brain stem cells that can turn into any number of specialized cells, these differentiated MGE cells have a specific function, which is to inhibit signaling in overactive nerve circuits. These experiments hold promise for future treatment of neurological disorders like Parkinson’s disease, Alzheimer’s, epilepsy, and the chronic pain and spasticity caused by spinal cord injury.
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Bioengineers at the University of California San Diego have come up with a novel way of removing dangerous toxins from the bloodstream using biomimetic nanosponges. These tiny clean-up particles work by posing as red blood cells, which serves both to evade the body's immune system response to foreign invaders and to attract the toxins to themselves instead of to actual red blood cells. When the toxins have all attached themselves to the nanosponges, they are processed out through the liver without harming the body. The research into this promising therapy comes out of the Zhang Lab in the Jacobs School of Engineering, where in 2011 they pioneered the red blood cell disguise technology for cloaking cancer drug cocktails, allowing the drugs much more time in the body to target diseased cells. Dr. Liangfang Zhang is also on the research faculty of the UCSD Moores Cancer Center.
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The California Institute for Regenerative Medicine (CIRM) is a major funding agency for stem cell research in the Golden State. Since voters approved the establishment of the agency in 2004, the CIRM has spent billions on research and facilities with the aim of making California the stem cell capital of the US. Now, in a move to advance that research mission even further, the agency has announced awards of $32M to investigators and stem cell companies to create a biobank of diseased cell lines for the use of researchers around the world. Called the Human Induced Pluripotent Stem Cell (hiPSC) Initiative Awards, the project will generate and ensure the availability of high quality disease-specific hiPSC resources for disease modeling, target discovery and drug discovery and development for prevalent, genetically complex diseases.
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