Researchers at Washington University in St. Louis have received an immense amount of additional funding from the National Institute on Aging to assist them on the first large-scale clinical trial to study Alzheimer's disease that is underway. This clinical trial, called the Dominantly Inherited Alzheimer’s Network Trials Unit (DIAN-TU) will work with people who have dominantly inherited forms of Alzheimer's to identify new drugs that can slow the onset of the disease, or stop it altogether.
Beginning with $5.5 million in funding this year, the trial will continue to receive funding from the NIH over the next five years to total $26 million. The National Institute of Aging has been supporting this research since 2012, when the project began. This new funding will allow the trial to add an additional 300-400 participants to the study, as well as assist the research team in adding new drugs to the study. The trial is being run in locations in the United States, Canada, Europe, and Australia, and this funding will help add 10-15 more locations.
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In the process of growing and studying neurons in the lab, life science researchers often use flat platforms or dishes. But neural networks in the body don’t lie on a flat plane or platform. A research team from the University of Illinois, Urbana-Champaign decided to add a new dimension to neuron study by developing a 3D environment to study neural networks.
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As the largest state in the continental U.S. and the second most populous state of all 50, it is no wonder that the Lone Star State is known for being BIG. Amongst the big things in Texas are three world-class research institutions: University of Texas Austin, Texas A&M University in College Station, and Texas Medical Center in Houston.
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Athens, Ga. - Susan R. Wessler of the University of California, Riverside has been awarded the McClintock Prize for Plant Genetics and Genome Studies, an honor given annually by the Maize Genetics Executive Committee, or MGEC. 
The announcement was made Oct. 28 by Jeff Bennetzen, MGEC member and the Norman and Doris Giles Professor of Genetics and Georgia Research Alliance Eminent Scholar at the University of Georgia.
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Sepsis, the leading cause of death in hospitals throughout the United States, is caused when someone has a severe reaction to germs and bacteria. It often occurs as a complication to an infection or a surgery, when the immune system has been weakened and is unable to fight off bacteria. Considering how frequently sepsis occurs, it is surprising how under-represented it is in health talks and research. One researcher at the University of California Santa Barbara was recently awarded a $3.5 million grant from the NIH Heart, Lung and Blood Institute to continue his work on increasing sepsis survival rates. (Image on right courtesy of Wikimedia).
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One of the most baffling and crippling sorts of diseases are those that incite the immune system to attack the body. This class of diseases, known as autoimmune diseases, may seem like a very specialized and rare affliction, but in truth, it manifests itself in the form of several commonly known ailments like rheumatoid arthritis, asthma, type 1 diabetes, and multiple sclerosis. A new study from the University of California, San Francisco points to some of the causes and thus possible treatments for autoimmune diseases.
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There are thousands of genes in the human genome that all have different purposes. At least 3,000 of these genes are known to express proteins that can be altered by different medications, however, the FDA has only approved drugs that target around 10 percent of these genes. That means that there are still thousands of genes that have not been thoroughly studied that, with the help of the right medication, could be targeted to help improve human health. The National Institutes of Health Common Fund has awarded 8 U.S. institutions $5.8 million for a new collaborative three-year program called Illuminating the Druggable Genome (IDG) that will study different genes and their potential to be modified by different medicines.
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There are currently 14 operating Proton Therapy Treatment Centers around the United States, and in 2015 a new center in Baltimore will be completed. The University of Maryland Baltimore, in collaboration with Advanced Particle Therapy LLC of San Diego, began constructing a $200 million Proton Therapy Cancer Center in 2012 that is on track to begin treating patients in 2015. Once completed, the new center will be the first Proton therapy Center in the Baltimore-Washington area, and only the 5th center of this type on the East Coast.
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After undergoing cancer treatments such as chemotherapy, many people experience a lapse in memory, known as chemo brain. Along with memory problems, chemo brain can also include having trouble concentrating, taking more time to finish simple tasks, and having trouble multi-tasking. The cause of chemo brain is currently unknown, but researchers at the University of Texas Health Science Center in Houston (UTHealth) have recently discovered a possible cause of chemo brain. (Image on right courtesy of Wikimedia).
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There are many times when putting tarantula toxin into human cells seems like a very bad idea. At the University of California, Davis, however, it is a breakthrough idea that allows for closer examination of the electrical activity in cells, especially neurons. This opens up the field of brain study and also lends insights into conditions like muscle defects, cardiac arrhythmias, and epilepsy.
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