A new study at the University of Pennsylvania, published in the journal PLOS ONE, has had researchers develop a variant of the mu opioid receptor that is water-soluble and can be grown in large quantities in bacteria. When the mu opiod receptor binds with opioid molecules, a strong reduction in the sensation of pain occurs. Unfortunately, fatal side effects can occur. According to a University of Pennsylvania news article, researchers at the university sought to address this issue by identifying the hydrophobic amino acids on the exterior of a structured model of the protein.
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Tags: 2014, 2013, Pennsylvania, Northeast, University of Pennsylvania, UPenn, Philadelphia, BioResearch Product Faire Event, PA, research news
Drexel University in Philadelphia recently created an entrepreneurship incubator that aims to fund and seed investment in companies ready to move into the market. According to MedCity News, the incubator will support medical and biotech startups along with a more diverse portfolio of startups.
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Tags: 2014, 2013, Pennsylvania, Northeast, University of Pennsylvania, UPenn, Philadelphia, BioResearch Product Faire Event, PA
University of Pennsylvania science researchers Jason Burdick and Robert Mauk recently published a study in the Proceedings of the National Academy of Sciences that sheds light on mesenchymal stem cells, a sort of adult stem cell located in bone marrow that is able to turn into fat, bone or cartilage cells.
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Tags: 2014, 2013, Pennsylvania, Northeast, University of Pennsylvania, UPenn, Philadelphia, BioResearch Product Faire Event, PA
A new study by researchers at the University of Pennsylvania has findings that suggest a new way ECMO, or extracorporeal membrane oxygenation, can help treat patients with shock and cardiac arrest. ECMO has been used in the past during cardiac surgeries as a way to replace patients’ heart and lung function. According to Health Canal, researchers at the University of Pennsylvania have made a breakthrough in using this intervention to save the lives of patients who are unable to be resuscitated.
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Tags: 2014, 2013, Pennsylvania, Northeast, University of Pennsylvania, UPenn, Philadelphia, BioResearch Product Faire Event, PA, university lab equipment, life science solutions, life science marketing event
The University of Pennsylvania’s Perelman School of Medicine announced the establishment of a new biomedical informatics program this March. The Institute for Biomedical Informatics (IBI) received founding support from the Smilow Center for Translational Research. According to Dr. J. Larry Jameson, dean of the Perelman School of Medicine, the Institute for Biomedical Informatics will "bring together the large number of Penn faculty who work in the broad field of biomedical informatics to inform science and medical care. We will expand the number of faculty even more to create a wide-ranging program of research and education to find and clinically apply the treatments of the future and to train the next generation of physician-scientists.”
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Science researchers at the University of Pennsylvania conducted a study that may help them reach a better understanding of health conditions such as arteriosclerosis, aneurysms and thrombosis. The results of the study are making the news as one of a number of compelling current science events at the University of Pennsylvania. According to science researchers, blood plasma is thicker and more elastic than water. Depending on how much pressure blood plasma is under, it flows differently under different circumstances, meaning that blood plasma influences how blood flows more concretely than scientists thought in the past.
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Long considered one of the inferior senses, anyone who has lost their ability to taste as a result of age or cancer treatment will tell you life's luster is considerably dimmed in the absence of this sensory experience. Fortunately, research into taste and smell is going strong in Philadelphia at the Monell Chemical Senses Center, which is the only non-profit scientific basic research institute in the world dedicated entirely to understanding these intertwined senses. Once an entity within the University of Pennsylvania, the Center branched out on its own several decades ago, with labs a few blocks from the Penn campus on Market Street. Researchers at Monell work interdisciplinarily and many have joint appointments with Penn. Other research projects are carried out in conjunction with scientists at Thomas Jefferson University, also in Philly, and indeed with university and private lab investigators around the world.
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Tags: 2014, 2013, Pennsylvania, Northeast, University of Pennsylvania, UPenn, Thomas Jefferson University, Stem cell research, taste buds, Monell Chemical Senses Center, Philadelphia, BioResearch Product Faire Event, PA, ThomJeff, taste
The Parkinson's Disease Biomarkers Program (PDBP) is a recently-formed NIH initiative to advance research into biomarkers for the disease in order to better understand its progress and develop treatments. Some funded projects will focus on statistical analysis tools and data sharing among researchers. Others will examine early clinical manifestations of PD in patients. Still more will involve lab studies, including identification of genetic biomarkers as well as antibodies in the blood and changes in body chemistry. All projects "must inform the etiology, pathogenesis or treatment of PD," according to grant program guidelines. Research supported by the PDBP is being carried out at the 11 Morris K. Udall Centers of Excellence in Parkinson's Disease Research (logo right), directed by the National Institute of Neurological Disorders and Stroke (NINDS) within the NIH.
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Dr. Gary Michelson is a retired Los Angeles surgeon who made a lot of money ($1.35B) from a spinal surgical invention in 2005. Since then he's devoted himself and his considerable resources to philanthropy. One of his most passionate causes is reducing the rate of euthanasia for unwanted pets by promoting spaying and neutering, along with shelter adoption, training, and good vet care through the Los Angeles group Found Animals. Not content with the usual invasive practice of sterilizing pets, he also created the Michelson Prize and Grants to challenge research scientists to come up with a cheap, safe, and effective one-dose pill for cats and dogs to induce permanent infertility. The winner of the Michelson Prize in Reproductive Biology will take home $25M and the satisfaction of knowing that fewer pets will be put down because of overpopulation.
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With the advances in microscopy and digital imagery today, it's not unusual to find yourself looking at visual representations from the micro-world of the lab that are truly beautiful to behold, both for what they tell us about the science of life and on an aesthetic level as well. Some of the images might be said to qualify as art. In the case of Greg Dunn, PhD Neuroscience 2011 from the University of Pennsylvania, neural art has become his profession, and departments of neuroscience across the US have commissioned his large, metallic and ink visions for their offices, libraries, and reception halls. Influenced by Japanese art, completely self-taught, and still very much the scientist with his subject matter, Dunn's work is quite simply spectacular, and a great deal more than an homage to the neuron.
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