Researchers at the Columbia University Medical Center (CUMC) may have found a way to reduce brain damage caused by a stroke or stroke-like event. In a study funded by the National Heart, Lung, and Blood Institute and the National Institute of Neurological Disorders and Stroke, 10-day-old mice that had an hypoxic (lack of oxygen) or ischemic (lack of blood) brain injury were treated with a fat emulsion containing either DHA or EPA—omega-3 fatty acids. The researchers evaluated the mice’s neurological function 24 hours and 8 to 9 weeks after the brain injury. They discovered that the mice treated with the DHA omega-3 fatty acids had a significant reduction in brain injury. This did not hold true for those treated with EPA-omega 3. The DHA group also had significantly better results in multiple brain functions during the 8 and 9 weeks evaluation compared to the EPA-treated mice and the control group which went untreated.Read More
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New York's Columbia University is nearing the completion of an ambitious building project more than three years in the making. Columbia University Medical Center (CUMC) will open its new state-of-the-art building this August. Work began on this 100,000 square-foot, fourteen-story glass tower in September of 2013 thanks in large part due to a financial gift from Dr. Roy Vagelos and his wife Diana. So it seems fitting that the building will be named the Vagelos Education Center.
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Neuroscience and genetics are two important topics life scientists are consistently studying. Researchers from UC Davis found a promising treatment for Huntington's Disease, while UC San Francisco was awarded $185 million to build a new neuroscience research institute. Recently on the East Coast, a team of researchers from the Columbia University Medical Center discovered a new neurodevelopmental syndrome as well as the genetic makeup of the mutations that cause the syndrome. (Image courtesy of Allen Ajifo via Wikimedia Commons)
The human microbiome is a complex system of bacteria that live and interact in different tissues and organs throughout the body. This complex system is a growing area of focus for life science researchers looking to learn more about these interactions and functions. In order to help its researchers in this rapidly expanding field, Columbia University in New York has established both a working group and a new core facility to help increase research potential of the microbiome.Read More
The Herbert Irving Comprehensive Cancer Center (HICCC) at Columbia University Medical Center and New York Presbyterian Hospital is a growing, highly funded research institution that focuses on researching all aspects of cancers. Since it's establishment in 1972, the HICCC has continuously performed world-renowned research and clinical trials.Read More
Every year about 1 million surgeries in the United States are performed to repair torn meniscus, the protective cartilage in the knee. When this cartilage is damaged, it can cause pain and lead to serious arthritis. Current treatments to repair meniscus involve performing a transplant with tissue taken from either different areas in the body or from a cadaver,. This method, however, has significant risks and relatively low success rates.Read More
If significant research is any indication of the quality of lab sales leads at life science marketing events held on Columbia University’s campus, this next story is worth reading about. Columbia University Medical Center researchers conducted a significant study that has identified a number of metabolic expression changes in the gene expression data from 22 tumor types. The analysis also points to hundreds of medications that could remove a tumor’s fuel supply or inhibit a tumor’s synthesis. The study was published in Nature Biotechnology.
A $20 million gift from Philip and Cheryl Milstein to the Columbia University Medical Center was announced recently. The donation will be used as part of an effort to rejuvenate the medical campus with construction of the Medical & Graduate Education Building on Haven Street between West 171st and West 172nd Streets. Administrators at Columbia University Medical Center said the building will include “innovative classroom and study spaces that will incorporate state-of-the-art information technology while facilitating collaborative, team-based learning.” The new building’s function will be the training of students in the College of Physicians and Surgeons and the biomedical science departments in the Graduate School of Arts and Sciences. (Read our earlier blog on this new construction project at CUMC here.)
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Dr. Thomas Jessell is a developmental neurobiologist at Columbia University Medical Center and the latest recipient of the Scolnick Prize in Neuroscience, which includes a $100,000 award. In the Jessell Lab in the Hammer Health Sciences Building, researchers study the vertebrate central nervous system to understand how neurons become encoded at the embryonic level, particularly in the spinal cord. The Scolnick Prize singles out Jessell's work for identifying signaling molecules and transcriptional code that establish a linkage between functional circuitry and motor behavior. Also a member of Columbia's Motor Neuron Center, which is dedicated to the study of motor neuron diseases like ALS, Dr. Jessell is a faculty member in the Department of Biochemistry and Molecular Biophysics, a Howard Hughes Medical Institute investigator, and part of the larger Columbia Neuroscience interdisciplinary research community. He will travel to Boston in April to accept the prize and deliver a lecture (see image at right). The Scolnick Prize is given out by the McGovern Institute for Brain Research at MIT. According to McGovern chairman Robert Desimone, from a recent CUMC press release:
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The Brain Activity Map project could be the next big federal life science research endeavor, with no less a goal than the mapping of the entire living brain and all its neuronal activity. Like the Human Genome Project of the 90's, the not insignificant financial outlay is being presented as an investment that will net even bigger returns, both in terms of new technology and a vastly increased understanding of the mind. President Obama is expected to include the multi-billion dollar, decade-long funding in his upcoming budget proposal, and neuroscience research was a topic he addressed specifically in his recent State of the Union address.
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