Malaria and toxoplasmosis are caused by different, yet closely related, apicomplexa parasites. Efforts to eliminate these diseases have met with only partial success. Now the National Institute of Health (NIH) has awarded the University of South Florida (USF) a $2.5 million, five year grant to study a new approach to fighting these diseases by stopping their ability to replicate.
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Researchers at the Columbia University Medical Center (CUMC) may have found a way to reduce brain damage caused by a stroke or stroke-like event. In a study funded by the National Heart, Lung, and Blood Institute and the National Institute of Neurological Disorders and Stroke, 10-day-old mice that had an hypoxic (lack of oxygen) or ischemic (lack of blood) brain injury were treated with a fat emulsion containing either DHA or EPA—omega-3 fatty acids. The researchers evaluated the mice’s neurological function 24 hours and 8 to 9 weeks after the brain injury. They discovered that the mice treated with the DHA omega-3 fatty acids had a significant reduction in brain injury. This did not hold true for those treated with EPA-omega 3. The DHA group also had significantly better results in multiple brain functions during the 8 and 9 weeks evaluation compared to the EPA-treated mice and the control group which went untreated.
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