Polycystic Kidney Disease (PKD) is considered to be one of the most fatal genetic diseases that affects more then 500,000 people in the United States. This disease, caused by a mutation in certain genes, causes the growth of cysts on the kidneys, which lead to kidney enlargement and failure. The are currently no treatments to permanently cure or halt the progression of this disease. Current solutions for PKD are receiving either a kidney transplant or staying on dialysis for the rest of ones life, neither of which are ideal situations.Read More
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Researchers at the University of California, Santa Barbara recently conducted a study on fruit flies that shows that diet experience can alter taste preference. This finding has been speculated about before, but its implications now are important because taste preference is essential for survival when animals and humans are forced to respond to changing sources of food. The researchers exposed fruit flies to camphor, which the fruit flies disliked, and which caused a reduction in the response by the Transient Receptor Potential-Like (TRPL) channel. The degredation of the TRPL protein by an enzyme called E3 ubiquitin ligase, or Ube3a, caused a reduction in the fruit flie’s distaste for camphor.
Researchers are invited to UCSB BioResearch Product Faire. There’s no better way to learn about the latest lab technologies on the market and socialize with colleagues at the University of California, Santa Barbara than to attend Biotechnology Calendar, Inc.’s upcoming Santa Barbara life science event on April 1st, 2014. At the Santa Barbara BioResearch Product Faire™ Event, you will have the opportunity to meet other researchers and lab supply sales reps interested in hearing about your research processes. Biotechnology Calendar, Inc. events bring high quality vendors to your doorstep and helps you find products that meet your research needs.
Yesterday we looked at two biologically inspired engineering experiments out of the Wyss Institute in Boston. Today we're on the West Coast at the University of California Santa Barbara's Institute for Collaborative Biotechnologies (ICB) marvelling over another technology that takes its cue from the biological world. It's a microfluidics device designed to function much like the super-sensitive nose of a dog, and it's already being commercialized for use in bomb detection, though other applications could include bio/chemical detection in industrial and healthcare settings as well. Results of the research gauging bomb detection accuracy specifically were published recently in an article in the journal Analytical Chemistry.
The California Institute for Regenerative Medicine (CIRM) has just celebrated the opening of its latest state-of-the-art research labs, at UC Santa Barbara's Center for Stem Cell Biology and Engineering. The new labs are located in the Bio II Building next to the Life Sciences Building on the eastern edge of campus. The 10,000sf, $6.4M wholesale renovation has taken about 5 years to go from concept to full realization. All funding came from CIRM or private donations, to allow faculty the flexibility to study the full range of stem cell technologies, without regard to federal funding limitations. The new Center is part of the Neuroscience Research Institute at UCSB.
Anyone who's ever pulled an all-nighter to finish a project knows how it wreaks havoc with your metabolism. The fact is, it's not just a nicety to be awake and active during the day and sleep at night: it's the way bodies are hard-wired. Scientists have long-suspected that upsets in a person's biological clock could play a factor in the development of metabolic disorders like diabetes. Now a team of researchers from three Southern California universities has made surprising discoveries that support that hypothesis. Not only have they isolated the protein that regulates the biologic clock (and named it cryptochrome), but they have found a molecule called KL001 that dictates when cryptochrome gets sent to the proteasome recycling bin. Which is to say, they now know a lot more about this complex circadian system that not only tells the body when to sleep and wake, but also how the body should manage glucose levels in those periods of relative activity and dormancy. The bio research study was published in the July 13 advance online issue of the journal Science.
Tags: California, CA, Southwest, NSF, Scripps, University of California San Diego, University of California Santa Barbara, University of Southern California, biology research, Diabetes, Los Angeles, Biochemistry, bio research, 2012, Front Line event, USC
Oracle Corporation is a Northern California computer technology giant with its world headquarters in the San Francisco Bay Area's Silicon Valley. From its wildly popular OpenWorld tech conference event held annually in San Francisco to its America's Cup sailboat that can be seen tacking across the Bay to and from the Golden Gate Yacht Club on a nice day, Oracle maintains a strong presence in the Bay Area, even beyond its extensive Redwood City campus. But that doesn't mean the company's Chairman of the Board (and former CFO) Jeff Henley lacks the vision to see that one of California's great strengths as far as technology goes is in the University of California System, and that strength comes from leveraging its power and resources across the state. That's why Henley and his wife have just committed $50M to fund a new science building, labs and faculty salaries on the UC Santa Barbara campus, where Henley got his undergraduate education.
Waste is an inevitable bi-product of human life, industry, and agriculture. One of the scientific challenges we face as a society is managing that waste and minimizing its deleterious effects on the environment that we depend upon for current and future sustenance. This ecosystem management increasingly involves the utilization of life science processes whereby good bacteria eat the unwanted effluent and render it neutral or even beneficial through an organically bioactive treatment system. This process is called bioremediation, in contrast to chemical sterilization systems (e.g. chlorination) that can cause problems downstream.
UCSB's Center for Energy Efficient Materials (CEEM) was launched in August 2009 with $19million in funding from the Dept. of Basic Energy Sciences, a branch of the DOE. CEEM's mission is to help solve some of the world's most pressing energy problems, drawing on UCSB's strength in materials science research.