Osteoporosis affects a large portion of the population in the United States. According to the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), over 52 million people currently have osteoporosis or are at the risk of getting it in the future. With such a high amount of people affected, many treatments have been used on patients suffering from bone loss. However, the current treatments for this disease have been linked with an increased risk of getting infections and certain types of cancers later on. Researchers at Washington University in St. Louis have recently discovered a way to create treatments for osteoporosis that lower the risk of aftereffects.
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When it comes to fighting bacteria, it’s all about understanding the enemy. Bacteria are especially good at rapidly dividing; in fact, they are more efficient than cells at self-replication. Microbiologists at the Washington University, St. Louis decided to go straight to the root of the problem and find out how to turn bacteria into zombies that can’t reproduce.
The first step in shutting down bacterial replication was determining just why bacteria are so good at it, instead of just taking the fact for granted. Petra Levin (left), associate professor of biology at WUSTL, notes that “people spoke of the bacterial cell cycle as somehow magically coordinated even though there was no mechanism for doing so. Things just somehow worked out fine even though no control system had been identified.”
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When it comes to creatively solving problems in biotechnology, time and time again nature takes the cake. In our recent history, we’ve seen the University of Minnesota use the kava root to prevent lung cancer and Michigan State University take cues from a mouse to develop new anesthetics. Now researchers at University of Washington, St. Louis are looking to nature to solve a problem where biotechnology is at its wit’s end: developing an effective antibiotic.
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The most deadly and contagious strain of malaria actually isn’t found in Africa- it makes its home in Southeast Asia and South America. Plasmodium vivax, as the strain is known, has been a worldwide challenge to treat and prevent. However, thanks to groundbreaking lab work from Washington University in St. Louis, researchers are developing an understanding of how this form of malaria works and what can be done against it.
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Determining the causes behind Alzheimer’s disease is a difficult task. Symptoms appear seemingly without provocation, and scientists have been so far unable to pinpoint a clear reason for their onset. Now bioresearchers at Washington University at St. Louis have found a possible explanation, in the form of a gene that regulates our internal clock.
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Researchers at Washington University in St. Louis recently received a great deal of life science research funding for leukemia research. The National Cancer Institute, part of the National Institutes of Health (NIH), gave the university two grants totaling $26 million. The money will be given to leukemia researchers and physicians at Siteman Cancer Center at the Washington University School of Medicine, according to St. Louis American Local News.
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One of the current trends in life science research is to find the microbes behind the processes and phenomenon with which we’re already familiar. Once we understand the role that bacteria play, we can replicate, enhance, or halt their methods as we need to. Such is the case at the Washington University at St. Louis, where bioresearchers are better understanding the microbes in our intestines in order to take a stab at obesity.
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Physical adaptation is usually thought of as a very slow process. It might take a species of bird several generations to evolve a beak suited for eating fruit compared to, say, pecking wood. This change would involve the death of several birds with “incorrect” sets of genes and the survival of one type of bird with a “correct” set of genes. But what if a creature had a huge library of genes, so that they might bypass natural selection by simply expressing the right genes for their environment? That’s what researchers at Washington University at St. Louis have found occurs in the versatile fire salamander.
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Lab suppliers trying to market university lab equipment and life science solutions may be interested in increasing scientific product sales at Washington University, given the school’s announcement that it will build a new medical building. It’s expected that the $75 million research building will break ground this summer and possibly be completed by June 2015. The facility will be dedicated to interdisciplinary research on the most complicated problems in human biology. Some of the life science disciplines already slated to be located within the building include genetics, genomics and regenerative biology. The facility will also be LEED certified.
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