Every year about 1 million surgeries in the United States are performed to repair torn meniscus, the protective cartilage in the knee. When this cartilage is damaged, it can cause pain and lead to serious arthritis. Current treatments to repair meniscus involve performing a transplant with tissue taken from either different areas in the body or from a cadaver,. This method, however, has significant risks and relatively low success rates.
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The University of Maryland, Baltimore Institute for Genome Sciences (IGS) recently received a grant of $15.2 million from the National Institute of Allergy and Infectious Disease (NIAID) to establish a new research center. This 5 year award will be used to establish the IGS Genome Center for Infectious Diseases.
The new center will be led by an interdisciplinary team of University of Maryland, Baltimore researchers from the Institute of Genome Sciences, Department of Microbiology and Immunology, and the Center for Vaccine Development who will study pathogens and their hosts using different genomic techniques to gain a better understanding of how pathogens cause harm. In the IGS Genome Center for Infectious Diseases, researchers will be able to study pathogen biology, virulence, drug resistance, immune invasion, and host-microbiome interactions using different genomics and bioinformatics approaches. (Image courtesy of Wikimedia).
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A team of neuroscientists at Rockefeller University in New York have developed a new method of imaging the brain and other large biological samples, called iDISCO, that allows researchers to see molecular complexities within these samples in 3-D.
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Premature birth, babies born before 37 weeks, can cause serious health problems for the half a million babies born early every year in the U.S. Health risks for premature babies include cerebral palsy, learning disabilities, vision and breathing problems, and hearing impairment. There are many different factors that can lead to preterm birth, but most of these factors are poorly understood. Further research is clearly needed to help better understand the causes of premature birth to lead to preventative methods. The March of Dimes Foundation of Philadelphia recently announced that it will donate $10 million over five years to establish a new Prematurity Research Center at the University of Pennsylvania. (Picture on right courtesy of Jennifer of Biotechnology Calendar, Inc.)
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Researchers at the Icahn School of Medicine at Mount Sinai University in New York have been studying how stress on fetal development is affected by different environmental toxins. The National Institute of Environmental Health Sciences (NIEHS) recently awarded Mount Sinai professor and researcher Manish Arora, BDS, PhD, MPH a $1.5 million New Innovator Award to help him continue this research. (Image on left courtesy of Wikimedia)
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Microbes, also known as germs, are found everywhere in the human body. Some are bad for health, some are good, and some still have unknown purposes. When the germs in the body cause an illness to set in, it is common to take antibiotic drugs to fight off the bad microbes making you sick. There are hundreds of types of antibiotics that cure different infections, but one thing all these antibiotics have in common is that they kill off all microbes, both good and bad. Life science researchers at Rockefeller University in New York have been working on creating 'programmable' antibiotics that will be able to target specific germs instead of attacking all of them.
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There are currently 14 operating Proton Therapy Treatment Centers around the United States, and in 2015 a new center in Baltimore will be completed. The University of Maryland Baltimore, in collaboration with Advanced Particle Therapy LLC of San Diego, began constructing a $200 million Proton Therapy Cancer Center in 2012 that is on track to begin treating patients in 2015. Once completed, the new center will be the first Proton therapy Center in the Baltimore-Washington area, and only the 5th center of this type on the East Coast.
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Glioblastoma is the most aggressive form of brain cancer, and like many other cancers, its causes are still unknown. Since it is generally very malignant, researchers know that glioblastoma cells frequently reproduce to keep the tumor alive and help it grow, and the location of glioblastoma in the brain provides the cells with ample blood supply. Through their study of glioblastomas, researchers at Columbia University Medical Center recently discovered that the gene KLHL9 is a leading factor in the cause of glioblastomas.
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Among Rockefeller University’s new life science funding is a $2.4 million grant from the NIH that will be used to fund a study involving integrating innate and adaptive pathways in vaccine response. The funding organization within the NIH that awarded this life science grant is the National Institute of Allergy and Infectious Diseases, and the project start date was April 1st, 2014.
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A new $25 million research fund has been established at Rockefeller University to aid in new techniques for drug discovery. The Robertson Therapeutic Development Fund was created in light of a generous $25 million gift from the Robertson Foundation, established by investment manager Julian H. Robertson, Jr. and his family.
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