Last month Chanwoo Park, assistant professor of the Department of Mechanical Engineering at the University of Nevada, Reno, received a five-year, $400,000 CAREER award from the National Science Foundation.
Researchers from University of Minnesota, Twin Cities have been working with a team of researchers led by Professor Sangeeta Bhatia from MIT to successfully develop a novel approach to diagnostic testing for non-communicable diseases, such as cancers and cardiovascular diseases.
The traditional diagnostic tests for cancers or cardiovascular diseases are stressful, time-consuming and expensive because these tests lack of reliable and easily detected biomarkers that signal the presence of diseases or conditions.
The groundbreaking diagnostic test that was developed by the researchers at the University of Minnesota has only two steps. After an injection of iron nanoparticles, a urine test that uses paper strips, which look like those found in a home pregnancy kit, will be used for detecting the biomarkers for the cancer or other condition.
Researchers found that both tumors and clots contain elevated levels of certain enzymes. In clots, the enzyme thrombin is elevated and cleaves a protein in order to release the “building block” molecule of clots; in tumors, a certain type of “protease” enzyme is elevated and cleaves a different protein that acts like a mini-machete to help release cancerous cells into the bloodstream.
Researchers combined two molecules into the iron nanoparticles, which would act as a “messager” to tumors and clots. One molecular was a synthetic analog of the protein or the enzyme of tumors and clots. Connected to it was the second synthetic detecting molecule, which would be set free to signal the presence of tumors or clots and would end up in the urine.
After injecting the iron nanoparticles into the mice, the researchers collected their urine and exposed it to strips of nitrocellulose paper coated with antibodies. As the urine flowed along a strip, it encountered strips containing antibodies that recognized tags associated with the second molecule. If any strip became visible, it meant tumors or clots were present.
This novel approach of diagnosis of tumor or cardiovascular disease gives doctors an advantage to diagnose easily and earlier. It is also a cost-effective way for patients to spare them from an expensive MRI.
Many of the materials in this diagnostic test, including iron nanoparticles, have been approved by U.S. Food and Drug Administration. University of Minnesota, Twin Cities has been planning to perform clinical trials and commercialize the technology.
These cutting edge research programs make the University of Minnesota one of the leading research institutions in the nation. Researchers at the University of Minnesota are eagerly looking for the newest products and technologies to fully develop their research. Over the past five years, inventions from the University of Minnesota researchers have generated nearly $274 million in revenue for the state of Minnesota.
University of Minnesota Twin Cities is also a richly funded marketplace. The University has received 606 grants and awards of over $263 million from the National Institute of Health in 2013 in addtion of 179 grants of $67 million as of April 24th 2014.
Biotechnology Calendar, Inc. helps laboratory supply companies to get their products and technologies into the UMinn’s laboratory by providing an opportunity to gather lab supply companies and researchers together at the UMinn Twin Cities BioResearch Product Faire™ Event. The next event will be held on May 20th 2014.
Tags: 2014, cancer research, University of Minnesota Twin Cities, UMinn
This month the University of Minnesota is opening a new state-of-the-art research building on Twin Cities campus. The new Physics and Nanotechnology Building will house the University College of Science and Engineering’s School of Physics and Astronomy as well as the Minnesota Nanotechnology Center.
Tags: 2014, University of Minnesota, UMinn, research facilities
Breast Cancer is one of most common cancers in American women. About 1 in every 8 women in the United States will develop invasive breast cancer during their lifetime. It is estimated that 232,340 new cases of invasive breast cancer will be diagnosed every year, and 39,620 women will die from breast cancer in 2014. It is crucial to take steps to prevent this deadly disease.
Tags: 2014, Thomas Jefferson University, cancer research, ThomJeff
In order to train students for a career in the rapidly growing biotechnology industry, Ohio State University has been working with several biotech companies to run a new program in the Department of Chemistry and Biochemistry.
Tags: 2014, Ohio State University, Biotech industry news articles, OhStu
Professor David Ruzic, PHD, director of the Center for Plasma Materials Interactions, gives a 5 minute overview of Plasma Physics at the University of Illinois, Urbana-Champaign. Althought this video was designed as a plug for the programs at Urbana, we found it a good overview for a non-physicist... we hope you will too.
Tags: 2014, University of Illinois Urbana-Champaign, UIUrbana
About one-third of the global population, more than 2.3 billion people, is infected with latent tuberculosis. TB, which is one of the world’s deadliest diseases, can remain dormant for years without being detected. Robert Abramovitch, MSU Assistant Professor of Microbiology and Molecular Genetics, has genetically engineered a protein that glows green when tuberculosis enters its latent stage. Abramovitch's work is a triumph that promises to find a faster-acting cure for TB.
Tags: Michigan State University, 2014, Research Funding, MSU
You are invited to show UCLA researchers how your lab equipment and supplies can help them meet their research goals for 2014, at the 33rd Semiannual Los Angeles Biotechnology Vendor Showcase™ Event at UCLA, which takes place on Thursday, April 3, 2014. Only 16 days away, you can join other top lab suppliers in providing this active market with the tools and equipment necessary for the world-class research that happens at UCLA.
Tags: 2014, CA, Los Angeles, LAVS
If you present, organize or attend scientific meetings, seminars or symposia, take advantage of our online meeting resource. Global science meetings is a place where you can post or access meeting information for free. This is a simple format open access science meeting portal that is powered by Biotechnology Calendar, Inc.
Tags: 2014, Research Symposia, SDVS
Increasing research product sales and selling scientific equipment at Georgetown University is made easy by exhibiting with Biotechnology Calendar, Inc. The best way to boost your vendor show sales is to register for marketing events with one of the most established names in the life science marketing business: Biotechnology Calendar, Inc. has been organizing lab product expos at top-funded research marketplaces for over twenty years. Spaces for our Georgetown Event are limited, however, so make sure to register for this event soon. Currently, we have 9 spaces left.
Tags: 2014, Georgetown University, Washington DC, D.C., Geotwn, product show