Posted by BCI Staff on Wed, Oct 19, 2011
The NIH recently awarded more than $110M in research funding for the second phase of the Knockout Mouse Project (KOMP), a phenotyping project involving an international consortium of researchers (the IKMC) who will generate about 5,000 strains of knockout mice that will undergo a large battery of clinical phenotype tests to reveal how traits are affected by deleting a given gene in an individual mouse.
Knockout mice are genetically customized mice that have individual genes turned off or have a gene ramped up, to make them either more prone or more resistant to specific diseases.
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