An estimated 15 million Americans will develop Alzheimer’s disease by 2060, according to researchers at the UCLA Fielding School of Public Health. The December 2017 study is the first of its kind to estimate the numbers of Americans with preclinical Alzheimer’s disease.
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Researchers at the University of California, Santa Barbara have discovered the age and origin of an E280A gene mutation that has caused early-onset Alzheimer’s in a Columbian family. The family, whose members have had Alzheimer’s with more frequency than most families, was traced to a single founder dating from the 1500’s. The research team sequenced the genomes of more than 100 family members and identified the regions of common ancestry. They then used this information to trace the source of the Alzheimer’s mutation.
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