Science Market Update

Principal Investigator’s Name

Project Titles or Description

Funding 

OJO, AKINLOLU OLUEUN

Health All of Us Research Program

$12,000,000

With one million participants, this will be the largest health database ever that researchers can use to conduct studies into how environment, lifestyle, and genes impact health

MARTINEZ, FERNANDO D

Early Origins of Chronic Airflow Limitations

OREX: Primary Prevention of Asthma in Children

$7,349,719

1^st Study follows up on Subjects in the Tucson Children's Respiratory Study who are now in their mid-thirties, a critical age during which early symptoms and functional manifestations of COPD first occur.

2^nd Study researchers will give a safe powder made up of detoxified pathogenic bacteria (Bronchovaxom) to infants at high risk for asthma, and determine if reduces the children’s odds developing persistent wheezing

BRINTON, ROBERTA DIAZ

Brain aging and Alzheimer’s Research and Therapy

$4,257,797

6 different research projects regarding how the brain ages, Alzheimer’s and related dementias, as well as a study into the use of a promising regenerative medicine, Allo, which activates the brain's own regenerative ability while reducing the pathology of Alzheimer’s

GARCIA,

JOE G. N.

Cytoskeletal Regulation of Lung Endothelial Pathology

$2,336,280

Research project focused on the critical role of the endothelial cell cytoskeleton in the pathobiology of acute respiratory distress syndrome (ARDS) which affects over 200,000 U.S. patients/year with a mortality of 30-35% 

BARNES, CAROL A.

Neurobiology of Aging

$2,246,292

4 different projects including research into the neurobehavioral relations in senescent hippocampus, gene expression supporting successful cognitive aging, brain adaptation, and neurobiology of aging and Alzheimer’s Disease

CHERRINGTON, NATHAN J

Southwest Environmental Health Science Center

$1,830,476

This center works for the advancement of environmental research related to arid environments through the organization of three main research themes: 1) Environmental Exposures in Underserved Southwest Populations, 2) Environmental Lung Disease, and 3) Adaptive Responses to Environmental Stresses.

KRAFT, MONICA

Dysfunction of Innate Immunity in Asthma/

Advancing Severe Asthma Precision Therapy

$1,819,856

 Seeks to demonstrate that aspects of the host response which are surfactant protein A, Toll interacting protein  and palmitoyl-oleoyl- phosphatidylglycerol are dysfunctional in asthma. This could lead to therapies to resolve persistent inflammation.

GALGIANI, JOHN N

Valley Fever  Vaccine Research

$1,703,956

Valley Fever is a fungal infection found in the South West that causes 50,000 illnesses, and 160 deaths, each year. The goal of this proposal is to prevent this disease entirely by developing a vaccine

GRANZIER, HENK L.

 Titan in Skeletal Muscle Health/

Role of Nebulin in Muscles

$1,626,923

1st study seeks to understand how mutations in titin might cause muscle disease and gain insights into possible therapeutic approaches

2nd study focused on investigating Nebulin, a skeletal muscle protein that can cause the debilitating nemaline myopathy disease. 

GOODRUM, FELI

Cytomegalovirus Research

$1,332,366

3 different studies into viruses including two on Human cytomegalovirus (HCMV) which is a persistant pathogen infecting the majority of the population worldwide. HCMV causes life-threatening disease in the immunocompromised

Arizona's BIO5 Institute: Over $1.3M in Grants for Ovarian Cancer Research

UC Riverside Receives Nearly $2.5M to Fund Cancer, ALS Research

$20M Gift to Establish New UCSF Center for Mood Disorders