“Despite the clinical success of antiretroviral therapy (ART), more people contract human immunodeficiency virus (HIV) infection daily than initiate ART,” states the NIH RePORTER abstract for a new study receiving funding from the NIH. “The difficulties of lifelong ART - particularly in the developing world - make the eradication of HIV imperative. But clearance of a retroviral infection for patients on ART is a herculean task. While much is known about HIV persistence despite ART, many puzzles remain. New tools to address latent infection must replace the paradigms and models used to develop ART.”
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A dangerous situation presents itself when bacteria evolve defenses against antibiotics. Experience has shown us that it can be a discouraging catastrophe for public health when a new drug-resistant strain, or a gene that confers resistance, shows up in a new place, as happened when the NDM-1 gene (which is resistant to up to 14 drugs) showed up in New Delhi drinking water. Scientists are searching for a way to defeat that debilitating resistance, however, and every so often there's encouraging news: On February 4, North Carolina State University chemistry researchers published a study in which they said that they’ve found a molecule that makes antibiotics 16 times more effective against recently identified antibiotic-resistant “superbugs.”
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