Science Market Update

Duke Scientists Use Zebrafish to Fight Deadly Brain Infections

Posted by Robert Larkin on Mon, Nov 23, 2015


Scientists at Duke Medicine are making significant headway in the study of Cryptococcal meningitis and its method of progression, thanks to the transparent zebrafish.

The unique, transparent nature of this delicate species of fish allows researchers to watch in real time as Cryptococcal meningitis moves through the tissue, blood vessels and into the brain of transparent zebrafish larvae.

According to the study, while usually treatable in the U.S. and other developed nations, meningitis brain infections are still responsible for more than 600,000 deaths annually. In order to more effectively target and treat the infection, researchers wanted to learn more about how meningitis moves from the lungs into the brain.

Enter the zebrafish -with its transparent body perfect for viewing the progression of meningitis, and the researchers of Duke University.

In the video above, researchers witness as red-dyed Cryptococcus fungi, made red by a fluorescent tracer, moves through tissue, blood vessels and into the brain. The video also shows blue macrophages working tirelessly to stave off the infection as it spreads through blood vessels (in green), and ultimately, into the brain.

In addition to studies of Cryptococcal meningitis, Duke researchers are also using zebrafish to study other disease-causing bacteria, such as those that lead to tuberculosis.

With life science projects like this one backed by over $1 billion in annual R&D funding, Duke University is a world leader in life science research. Life science events hosted by Biotechnology Calendar, Inc. and held at Duke University are fantastic venues for lab suppliers to meet and interact with its active and highly funded scientists.

If you would like to meet and discuss lab supplies with researchers from Duke Medicine and several other departments at Duke University, we invite you to attend the-

May 26th, 2016

04-dukeLast year, the Duke BioResearch Product Faire™ event hosted over 200 attendees, including purchasing agents, professors, post docs, and lab managers from 21 research buildings and 41 departments around campus. These are interested and engaged attendees, who are ready to discuss their lab needs with leading lab equipment suppliers. Early registration rates apply, so lab suppliers will want to act quickly to gain this added value at Biotechnology Calendar, Inc. shows.

To learn more about attending this annual event, including funding statistics from Duke University, click below:

Click Here to Get More  Duke Funding and Event Info

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Tags: East Coast Bioscience Shows, biomedical research, Medical Research, Duke University, North Carolina, disease research, Research Funding, Durham, NC, Duke, Southern Region, 2016, BioResearch Product Faire™, duke medicine

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