Spotlight on Science Meetings, Conferences and Events brings you information on the following: Keystone Symposia: Rigor in Science - The Challenge of Reproducibility in Biomedical Research to be held on 11/08/17.
Every researcher has a story about a compelling result that didn’t reproduce. Sometimes this is due to technical challenges or the experimental approach. However, there are also biological mechanisms that contribute to irreproducible results, and their importance is increasingly recognized by researchers, drug developers, funding agencies, and the general public.
In this discussion, we consider the issue of data reproducibility in preclinical research through a biological lens, focusing on often-neglected variables such as sex, age, microbiome, and circadian rhythms. The roundtable brings together stakeholders from across the biomedical enterprise to explore practical ways of controlling for these variables to maximize the translational potential of preclinical research. The participants include investigators Michael Holtzman, Dana Philpott, and Jeffrey Haspel, who encounter these variables in their research; Patricia Valdez, representing the NIH Extramural Research Integrity Office; and NPR Science Correspondent Richard Harris, who moderates the discussion and brings a lay perspective.
The goal of the discussion is to explore both the tensions and opportunities for exciting science that irreproducible results create in preclinical research. It also considers economical ways for researchers to address biological drivers of irreproducible results, to comply with new standards set out by funding agencies, and to enhance the potential of their work to lead to novel therapies.
Read More
Tags:
November,
Molecular Cell Biology,
Molecular Biology,
Life Sciences,
Conference,
2017,
Current Science Meetings and Events,
November 2017
Spotlight on Science Meetings, Conferences and Events brings you information on the following: Computational Image Analysis in Cellular and Developmental Biology to be held on 10/09/17 - 10/19/17.
Synposis: Topics covered in this course include: image enhancement, segmentation, tracking, feature extraction, image classification, machine learning including deep learning, noise analysis and uncertainty prediction, and statistical hypothesis testing. All topics will be covered in theory lectures and computer exercises. Exercises will be done on images from ongoing research projects in the instructors’ labs and will target actual research questions. An important subject in the course will be software design, addressing both the implementation of optimized algorithms and sharable code, and programming in teams.
Student requirements and course structure: The course will admit graduate students and junior postdocs with backgrounds in mathematics, physics, and/or engineering, who are currently conducting research in cellular and developmental biology. Students with no formal training in the quantitative sciences may also be considered if space is available and if initial experience in the practice of computer image analysis in microscopy is documented in the application. We will accept a maximum of 12 students. This size has been proven ideal since the first implementation of the course in 2011, and is also defined by the funds made available through an NIH grant. The course will be free for all admitted students, with the exception of travel expenditure to and from Woods Hole.
The course will contain two theory lectures per day. The rest of the course time will be primarily devoted to computer exercises under the guidance of the four course instructors and two TAs. To broaden the perspectives and encourage discussions, there will also be several evening seminars by invited faculty and by the students themselves.
The software projects will be done in small teams. This course structure is designed to train the students in the practicalities of code sharing and collaborative problem solving, allowing them to tackle complex image analysis problems when they return to their home institutions. At the end of the course, students will be encouraged to take home their own projects and the library code they integrated. The course will use MATLAB as the programming language, one of the most widespread platforms for scientific computing.
Importantly, this is not a course for students who wish to get familiar with MATLAB programming. On the contrary, we expect students to have basic knowledge of MATLAB (or solid expertise in another modular and/or object-oriented programming language), allowing them to start using Matlab on Day 1 for solving image and data analysis problems related to cell and developmental biology. Once the student body is identified, we will publicize tutorial materials for self-study.
Read More
Tags:
cell biology,
biological analysis,
Molecular Cell Biology,
Developmental Biology,
October,
Computational Biology,
life science research,
Life Sciences,
2017,
Current Science Meetings and Events,
October 2017
Spotlight on Science Meetings, Conferences and Events brings you information on the following: Mechanisms of Eukaryotic Transcription to be held on 8/29/17 - 9/2/17
The fifteenth meeting on transcriptional regulation in eukaryotes will be held at Cold Spring Harbor Laboratory from Tuesday evening, August 29 to Saturday afternoon, September 2, 2017. The program will consist of both oral and poster presentations. The oral presentations will be by a combination of invited speakers and speakers selected from amongst submitted abstracts.
Topics:
- Genomics
- Initiation / Activation
- Biophysical Mechanisms
- Elongation & Termination
- Regulatory Complexes
- Chromatin & Epigenetics
- Signaling & Regulatory Factors
Please bring this notice to the attention of any of your colleagues who may be interested in participating in the meeting.
Cold Spring Harbor Laboratory
Cold Spring Harbor, NY
https://meetings.cshl.edu/meetings.aspx?meet=MOET&year=17
Tuesday, August 29, 2017 to Saturday, September 2, 2017
Read More
Tags:
New York,
August,
Molecular Cell Biology,
Molecular Biology,
Cold Spring Harbor,
Life Sciences,
laboratory,
2017,
Current Science Meetings and Events,
August 2017,
Transcription
Spotlight on Science Meetings, Conferences and Events brings you information on the following: Next Generation Dx Summit 2017 to be held on 8/15/17 - 8/18/17
This summit convenes more than 1,000 international diagnostic professionals for valuable networking and comprehensive programming spanning from clinical diagnostics to business strategy. Now in its ninth year, the event has grown to include novel immunotherapy biomarkers, cell-free DNA, companion diagnostics, infectious disease, point-of-care, pharmacy-based diagnostics, clinical NGS assays, commercialization, reimbursement, prenatal testing, circulating tumor cells, critical care, forensics, digital PCR, microfluidics, and microbiome diagnostics. The Next Generation Dx Summit is a must-attend event with complete coverage of the most timely and important issues for the industry.
Read More
Tags:
Washington DC,
August,
Molecular Cell Biology,
Molecular Biology,
Summit,
Life Sciences,
District of Columbia,
2017,
Current Science Meetings and Events,
August 2017
Spotlight on Science Meetings, Conferences and Events brings you information on the following: Cellular Biology of Addiction to be held on 8/8/17 - 8/14/17
The primary objective of the proposed workshop is to provide an intense dialogue of the fundamentals, state-of-the-art advances and major gaps in the cell and molecular biology of drug addiction. Targeted to new or experienced investigators, the workshop will combine formal presentations and informal discussions to convey the merits and excitement of cellular and molecular approaches to drug addiction research. With the advent of genomics and proteomics, an extraordinary opportunity now exists to develop comprehensive models of neuroadaptative processes fundamental to addiction, withdrawal, craving, relapse to drug use and general brain function. A range of disciplines and topics will be represented, including noninvasive brain imaging to identify drug targets and adaptive processes; neuroadaptative processes at the molecular and cellular level, neural networks and their modulation, the relevance of genotype to susceptibility and drug response; tolerance and adaptation at the cellular level and approaches to exploiting the daunting volume generated by neuroinformatics. This workshop will provide an integrated view of current and novel research on neuroadaptive responses to addiction, foster discussion on collaboration and integration, provide critical information needed to construct a model of addiction as a disease and novel molecular targets for biological treatments. Beyond the plane of scientific endeavor, the information is vital for formulating public policy and for enlightening the public on the neurobiological consequences of drug use and addiction. This workshop is designed to generate interest in this level of analysis, open conduits for collaborations and present novel routes to investigating the neurobiology of addictive drugs.
Read More
Tags:
cell biology,
New York,
August,
Molecular Cell Biology,
Cold Spring Harbor,
Neuroscience,
Research,
laboratory,
2017,
Current Science Meetings and Events,
August 2017
Spotlight on Science Meetings, Conferences and Events brings you information on the following event: Molecular Mechanisms of Immune Cell Development & Function
Read More
Tags:
cell biology,
Immunology,
July,
Biology,
August,
Molecular Cell Biology,
Clinical Research,
Snowmass,
Life Sciences,
Colorado,
2017,
Current Science Meetings and Events,
July 2017,
August 2017
Spotlight on Science Meetings, Conferences and Events brings you information on the following event: Gordon Research Conference: Organellar Channels & Transporters
Read More
Tags:
cell biology,
July,
Biology,
August,
Molecular Cell Biology,
VT,
Vermont,
Life Sciences,
2017,
Current Science Meetings and Events,
July 2017,
August 2017
Spotlight on Science Meetings, Conferences and Events brings you information on the following event: Genome Engineering: The CRISPR / Cas Revolution
Read More
Tags:
New York,
July,
Molecular Cell Biology,
Molecular Biology,
Cold Spring Harbor,
NY,
Life Science,
2017,
Current Science Meetings and Events,
July 2017
Spotlight on Science Meetings, Conferences and Events brings you information on the following event: Ion Channel Regulation (2017)
Read More
Tags:
July,
Biology,
Molecular Cell Biology,
Molecular Biology,
Steamboat Springs,
Genetics,
Life Science,
CO,
Colorado,
Science Events,
2017,
Current Science Meetings and Events,
July 2017
Spotlight on Science Meetings, Conferences and Events brings you information on the following event: NAD+ Metabolism and Signaling
Read More
Tags:
July,
Molecular Cell Biology,
Molecular Biology,
Life Science,
Science Events,
Research Event,
2017,
July 2017
