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Regenerative Medicine: Transitioning Therapeutics from Cells to the Clinic

Posted on Jan 14, 2016 5:24:51 AM

Symposium - New York City, United States
The field of regenerative medicine is burgeoning with academic and industry groups, actively developing cell-based therapeutic products. These therapies aim to enhance or correct cell function, often utilizing genetic modification or gene editing approaches. Preclinical and early stage clinical trials have demonstrated that cell-based therapies can provide local and systemic clinical benefit by driving production and secretion of biologically active mediators such as cytokines and growth factors, reversing disease progression and promoting healing. Notably, cell-based therapies are already commercially available for cartilage injury and severe burn injuries, and clinical trials have shown promising results in diabetes, kidney disease, heart disease, stroke, cancer, spinal cord injury, and graft versus host disease (GVHD). To advance the development of cell-based therapies, next generation approaches for scaled manufacturing and formulation of cell-based therapeutic products are being implemented, enabling distribution demands in compliance with regulatory guidelines. Moreover, as numerous prospective therapeutics are targeted to clinical indications where there are no approved therapies, adaptive clinical trial strategies along with novel outcome endpoints for registration must be contemplated. These manufacturing and clinical endeavors require focused interactions between academia and industry to discover and translate key innovations in these areas. The symposium will unite key representatives from both academia and industry to discuss the challenges and important new developments critical for the advancement of the regenerative medicine field.
Organization: The New York Academy of Sciences
Mon, Feb 22, 2016 - Mon, Feb 22, 2016
The New York Academy of Sciences
New York City, United States
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Tags: Regenerative Medicine, infectious diseases, Medicine, United States, Symposium, February, Life Sciences, New York City, 2016

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