EMBO Conference: 'The DNA Damage Response in Cell Physiology and Disease'
Conference - Athens, Greece
The DNA damage response (DDR) is a complex signaling network including cell cycle checkpoints, DNA repair and damage tolerance pathways. The DDR is affected by – and in turn impacts on – myriad cellular components and processes, which include chromatin structure, DNA replication, telomeres, cell growth and cell-cycle status. Failure of the DDR or associated events causes genomic instability, an underlining cause of several human syndromes and also associated with various age-related diseases, particularly cancer. Notably, DNA damaging agents are also used in cancer therapy and drugs targeting DNA damage response enzymes are exhibiting an exciting potential as new anti-cancer agents.
The conference we propose will cover topics including:
DNA damage detection and signalling
Pathways of DNA repair
DNA replication
DNA damage response and the normal cell physiology
Chromatin structure
Ubiquitylation and related processes
Ageing, disease and therapeutic applications.
Organization: EMBO
(Courtesy of DNA damage response (DDR), via youtube.com)
EMBO Conference: 'The DNA Damage Response in Cell Physiology and Disease'
Mon, Oct 07, 2013 - Fri, Oct 11, 2013
Grecotel Cape Sounio, Athens, Greece
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