In the information age, cancer research is shifting from data generation to bioinformatics. This interdisciplinary field develops methods and software tools for understanding biological data. Bioinformatics combines computer science, statistics, mathematics, and engineering to analyze and interpret biological data. The Cancer Prevention & Research Institute of Texas (CPRIT) recently awarded W. Jim Zheng, Ph.D., of The University of Texas Health Science Center at Houston (UTHealth) a five-year, $5.8 million grant to sort through information that could lead to cures for cancer.
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Zheng, is the associate director of the Center for Computational Biomedicine at UTHealth School of Biomedical Informatics. In an article for TMC News, he stated, “The research into the causes of cancer using the latest technology has generated huge amounts of data. The challenge now is to sift through the sea of cancer research data to find cures.”
Despite advances in cancer research and treatment, cancer still claims approximately 1,600 lives every day worldwide. That’s nearly 590,000 people a year.
In hopes of changing this, Zheng is using the grant to establish the Data Science and Informatics Core for Cancer Research at UTHealth. This facility will have the big data infrastructure needed to identify links between cancer and other diseases. According to Zheng it will advance cancer research by making the latest computational methods to analyze cancer data available to scientists throughout the Lone Star State and then expand beyond state lines. He points out that digital health records are revolutionizing cancer research by making it easier for scientists to analyze big databases. One database alone includes 50 million patient records.
He goes on in the article to say that cancer research is moving from hypothesis-driven research to data-driven research and that mining the data will provide clues as to the causes of cancer. Zheng’s team has both the computer algorithms and computer storage – 1,000 terabytes – needed to analyze large data sets.
The new facility will be housed in the only freestanding school of biomedical informatics in the country. The UTHealth’s School of Biomedical Informatics, which is housed on the Texas Medical Center campus, works to improve health care and biomedical research by developing, refining and advancing the field of biomedical informatics through research, service and by training professionals in all areas of the discipline. It is home to five research centers: Computational Biomedicine, Precision Health, Gulf Coast Regional, National Center for Cognitive Informatics and Decision Making in Healthcare and the Biomedical Informatics Group
TMC is the largest medical complex in the world, with 54 medicine-related institutions. These include 21 hospitals and eight specialty institutions, eight academic and research institutions, four medical schools, seven nursing schools, three public health organizations, two pharmacy schools and a dental school. TMC is located in a 2.1-square-mile medical district and neighborhood in south-central Houston. It employs over 106,000 people, hosts 10 million patient encounters annually, and has a gross domestic product of $25 billion.
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