Antiviral RNAi: From Molecular Biology Towards Applications
Symposium - Pultusk, Poland
Viral diseases not only form a major threat for human health, but also have a detrimental impact in livestock and agricultural economic activities. RNA interference (RNAi) and RNA silencing are terms denoting an ensemble of regulatory pathways mediated by different families of small RNAs. RNAi is not only important because of its widespread physiological roles, but also because of its high potential as laboratory tool and therapeutic weapon. In this regard, RNAi-based strategies have been used to engineer plants that resist a large variety of viruses, and administration of antiviral small RNAs has been demonstrated to be highly efficient in inhibiting viral infections in mammals, and a number of clinical trials are currently ongoing to assess the safety and efficacy of this therapeutic strategy. The objective of the proposed conference is to review recent advances and to foresee future trends at the interface between RNAi and virus infection, covering the complete range from basic mechanistic RNAi to antiviral clinical trials.
(Photo courtesy of http://www.esf.org/index.php?id=9152)
Monday, June 11, 2012 to Friday, June 15, 2012
Polonia Castle in Pultusk, Poland
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