Symposium - Heidelberg, Germany
Many oncogenes and tumour suppressor genes have been identified and mapped to signaling pathways that regulate cell growth and death. Dysregulation allows oncogenes and tumour suppressor genes to transform mammalian cells and cancers arise in conditions where multiple such events occur in the same cell. It has also been found that a subset of the cells present in a tumour, called cancer stem cells, retain the ability to self-renew and to give rise to all cell types in a particular cancer.
An emerging concept is that tumours also strongly depend on external signals for maintenance and expansion. To fully understand tumour development and progression, a deeper knowledge of the cross-talk between tumour cells and their microenvironment and the interactions between cancer cells and cancer stem cells is needed.
Signaling pathways in stroma and cancers
Cancer stem cells
Cancer and the immune system
Animal models of cancer
Therapeutical implications: from bench to bedside
Organization: EMBO | EMBL Symposium
(Courtesy of EMBO/EMBL Symposium: 'Tumour microenvironment and - signalling' logo, via pinterest.com)
Wed, May 07, 2014 - Sat, May 10, 2014
EMBL Heidelberg, Germany
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