Workshop - Ma'ale Hachamisha, Israel
Homeostasis is critical for cellular and organismal functionality, survival, and lifespan. Organisms respond to environmental insults by activating transcriptional and post-transcriptional programs, which promote protein homeostasis (proteostasis). Proteostasis is regulated by several transcription factors including the heat shock factors (HSF), and the forkhead (FOXO) factors as well as by the unfolded protein response (UPR) and molecular chaperones, all also govern aging in various organisms. In this EMBO workshop we will cover recent developments in the field and explore the emerging links between stress resistance, proteostasis, the propagation of late-onset conformational diseases and the regulation of aging.
Sun, Sep 07, 2014 - Fri, Sep 12, 2014
Ma'ale Hachamisha Kibbutz Hotel, Israel
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