Symposium - New York, United States
Quantitative Systems Pharmacology (QSP) is a mathematical modeling approach to translational medicine that integrates quantitative knowledge about a compound with an understanding of its mechanism of action in the context of human disease. The goal of QSP modeling is "to understand, in a precise, predictive manner, how drugs modulate cellular networks in space and time and how they impact human pathophysiology". In the five years since the NIH QSP Working Group last met on this topic, there has been steady progress in both academic research and in the application to drug discovery and development. Despite these successes, full industry-wide adoption of QSP methods has yet to be realized. This symposium highlights advances in QSP applications in the continuum from preclinical exploration to clinical research and includes academic, government, and industry perspectives on the benefits and challenges of full adoption. Case studies from several therapeutic areas will be presented with applications to drug safety, efficacy, and precision medicine.
- Organization: New York Academy of Sciences
Tuesday, May 26, 2015 (8:30 AM - 4:30 PM)
7 World Trade Center, 250 Greenwich Street, 40th Floor,
New York, United States
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