Therapeutic vaccines: reprogramming immunity in infectious diseases, allergy and cancer
Metaphorically speaking the evolutionary driver for having an effective and highly regulated immune system could be equated to the historical need of human societies to protect themselves against foreign invaders (i.e. infectious disease); internal revolt (i.e. cancer) or a coup d’etat (i.e. allergy). However, as it is often described in the annals of history, compromises need to be reached in order to ensure a harmonious existence. Fortunately the immune system is well adapted to do just so. Accommodations are often made for the foreign invader to live with us (chronic infection/symbiosis). Battles might be lost in order to win the war (tolerance). Unintended damage might be caused in the heat of battle (autoimmunity).
The aim of this meeting is first to discuss the underlying cellular and molecular mechanisms that allow the immune system to respond to these diverse challenges while still remaining agile and adaptable. Another challenge will be to determine what factors play a key role in the failure of the immune system to keep under control such disturbances under specific circumstances.
Therapeutic vaccines: reprogramming immunity in infectious diseases, allergy and cancer
(Courtesy of Lake Annecy, France, via ewdastudent.wordpress.com)
Mon, Mar 25, 2013 - Wed, Mar 27, 2013
Les Pensières, Veyrier-du-Lac, Annecy (France)
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