Viral infection modeling provides insights into the pathogenesis and treatment of HIV, HCV, HSV-2, CMV and other viruses. It has had impact in revealing the lifespan of infected cells, how rapidly a virus is produced and cleared from the circulation, and the means for evaluating the effectiveness of antiviral treatments. Viral infections generally occur in tissues so the meeting will discuss imaging techniques and methods of modeling and analyzing spatial infection data, the role of tissue-resident memory cells, and important features of immune regulation, such as immune exhaustion, cytokine signaling between cells, and viral subversion of innate responses and escape from adaptive responses. The meeting will highlight significant hurdles to curing viral infections and will bring together experimental virologists, physician scientists and modelers of various types and experience.
Estes Park, Colorado, United States
Monday May 1, 2017 to Thursday, May 4, 2017