Science Researcher Update

EMBL Advanced Course: Next Generation Sequencing Data Analysis

Written by BCI Staff | Mar 6, 2013 4:03:00 PM

EMBL Advanced Course: Next Generation Sequencing Data Analysis

Course - Heidelberg, Germany

The large amounts of data derived from next generation sequencing projects makes efficient data mining strategies necessary. In the course you will learn strategies for the analysis of mRNA-Seq data as well as analysis pipelines for ChIP-Seq. These strategies include:

high efficiency mapping of raw sequence tags

clustering of sequence tags

data integration into up to date genome annotation

down stream analysis of tag covered regions

The course is based on real world examples. In the course you will use the Genomatix system for data analysis, which provides a graphical user interface. We will show the possibilities for comparative expression analysis, splice variant detection and discovery of new transcriptional units. In addition the down stream biological mining of enriched regions from ChIP-Seq will be demonstrated. This will focus on transcription factor (TF) analysis in terms of TF overrepresentation in enriched regions and the discovery of functional motifs and patterns of TFs. New insights into biological mechanisms can be gained by overlaying data from different experiment types.

 (Courtesy of EMBL building, Heidelberg, via microplate-readers.blogspot.com)

EMBL Advanced Course: Next Generation Sequencing Data Analysis

Tuesday, 23 April - Thursday, 25 April 2013

EMBL Advanced Training Centre, Meyerhofstraße 1, Heidelberg, Germany

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