Lyophilization Technology – Practical Application of the Scientific Principles
Course - Malvern, PA, United States
This course is designed to provide attendees with a practical approach to understanding the scientific and engineering principles of lyophilization. The topics discussed during the course will be presented to explain the physical, physicochemical, biochemical, and engineering principles of the science and engineering behind modern freeze-drying. The practicality of the course allows the attendees to get a firm understanding of the theoretical applications of freeze-drying and how these can be easily used and applied to their day to day lyophilization projects.
Topics covered will include:
•History of lyophilization
•Properties of water and ice
•Supercooling and supersaturation
•Phase behavior during freezing
•Thermal characterization
•Annealing
•Visco-elastic properties of amorphous phases
•Collapse phenomena
•Vacuum physics
•Product formulation
•Heat and mass transfer
•Cycle development
•End point determination
•Residual moisture
•Process scale-up and sonic water vapor flow
•IQ/OQ/PQ
•Process control and optimization
•Fault finding and problem solving of systems and formulations
•Freeze dryer mechanical and control systems
•Recipe development
•Following the process
This course has been pre-approved by the Regulatory Affairs Professionals Society (RAPS) as eligible for 12 credits towards a participant's RAC recertification upon full completion.
Organization: The Center for Professional Innovation & Education
(Courtesy of Freeze-Drying Technology, via americanlaboratory.com)
Lyophilization Technology – Practical Application of the Scientific Principles
Mon, Mar 24, 2014 - Tue, Mar 25, 2014
Desmond Hotel and Conference Center
1 Liberty Blvd., Malvern, PA 19355, United States
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