Science Researcher Update

Translation of Preclinical Drug–Drug Interaction & Metabolism Data into Risk Assessment of Clinical Toxicity

Written by BCI Staff | Oct 17, 2013 11:47:00 AM

Translation of Preclinical Drug–Drug Interaction and Metabolism Data into Risk Assessment of Clinical Toxicity

Symposium - New York City, United States

Drug discovery and development of new chemical entities now includes more assays to better predict human metabolism and potential for drug–drug interactions. However, translating the data from assays into more accurate predictions of the potential for human toxicity remains complicated. Metabolism and drug–drug interactions are not well modeled in preclinical animal studies, but better assessed using in vitro human cellular or protein assays. This symposium will assess new in vivo, in vitro, and in silico approaches to absorption, distribution, metabolism and excretion toxicity (ADME-Tox), and explores their integration to better interpret these data for the evaluation of human risk.

Organization: New York Academy of Sciences

Translation of Preclinical Drug–Drug Interaction and Metabolism Data into Risk Assessment of Clinical Toxicity

Mon, Oct 21, 2013 - Mon, Oct 21, 2013 (8:30 AM - 5:00 PM)

New York Academy of Sciences

250 Greenwich Street, 40th Floor, New York City, United States

If you'd like to ask a question or post a comment about this talk please do so below.

This seminar posting is brought to you by Biotechnology Calendar, Inc. providing access to research information and research tools for nearly 20 years. Visit our Science Market Update Blog for current science funding and market information or see our schedule of upcoming science research laboratory product shows.