Researchers at the University of North Carolina at Chapel Hill recently received a $3.5 million NIH award for their study “Gene Expression Patterns in Human Tumors Identified Using Transcript Sequencing.” The study is being led by Charles Perou, PhD. According to the University of North Carolina at Chapel Hill website, Dr. Perou is a distinguished professor of genomics at the university whose research interests include characterizing the biological diversity of human tumors using genomics, molecular genetics and cell biology.
The NIH RePORTER, which includes the details of the project’s abstract, says of the University of North Carolina at Chapel Hill researchers’ work:
“Gene expression provides a snapshot of the cellular changes that promote tumor malignancy. Quantitative gene expression analysis, especially as implemented by DNA microarrays, has proven to be an extremely valuable tool for cancer genome characterization, and has lead to the development of new genomic-based clinical tests. Our own experience with DNA microarrays to study gene expression patterns for breast, head & neck, and lung cancers has lead to the identification of novel subtypes of tumors with distinct patient outcomes and has identified new tumor suppressor genes. In the pilot phase of The Cancer Genome Atlas (TCGA) project, multiple platforms were used including tools to study gene expression (our role), tumor genomic DNA copy number alterations, SNP genotypes, DNA methylation and gene mutational analyses. Our collaborative efforts identified new tumor subtypes of glioblastoma and painted an integrated picture linking mutations to copy number changes to expression patterns, which identified biologically distinct subtypes of disease with differences in patient outcomes.”
Chapel Hill BioResearch Product Faire™ Event 2013
The University of North Carolina at Chapel Hill researchers also propose to continue to perform quantitative gene expression profiling, create global chromatin organization profiles of cancer to identify regions of "open" chromatin domains, and analyze transcript levels with chromatin stoicture to map important regulatory elements.
The University of North Carolina at Chapel Hill produces a number of groundbreaking studies every year. In addition to making this contribution to the study of gene expression patterns in tumors, the University of North Carolina is a well-funded market for lab suppliers interested in working to sell lab equipment and market lab products, according to recent NIH and NSF research funding statistics. In 2012, the NIH awarded the university $367.8 million in research funding. In addition to receiving NIH funding, the University of North Carolina at Chapel Hill also received $38.8 million from the NSF in 2012. Of that research money, $11.5 million went to life science projects alone.
Biotechnology Calendar, Inc. invites all lab suppliers interested in working to sell lab equipment and market lab products at North Carolina life science marketing events to attend our Chapel Hill BioResearch Product Faire™ Event. Last year, the Chapel Hill BioResearch Product Faire™ Event attracted 87 attendees, of which 37 were purchasing agents, professors and post docs, and 15 were lab managers. These visitors came from 14 different research buildings and 25 departments around campus.
Biotechnology Calendar, Inc. is a full-service science research marketing and events-planning company that has been organizing life science marketing events at top research institutions across the country for 20 years. If you are interested in marketing lab products or working to sell lab equipment at life science marketing events closer to home, we encourage you to view our 2013 calendar of events. For more detailed funding statistics on the University of North Carolina at Chapel Hill, or to learn more about the Chapel Hill BioResearch Product Faire™ Event, click on the button below.