Course - Cambridge, United Kingdom
This advanced course covers statistical methods currently used to map disease susceptibility genes, with an emphasis on (but not limited to) methods that can analyse family data or a combination of families and individuals. Discussions of the latest statistical methodology are complemented by practical hands-on computer exercises using state-of-the-art software. The statistical basics behind each method will be carefully explained so that participants with a non-statistical background can understand. With a focus on family data, we will discuss fundamental issues needed to increase success in gene mapping studies including: optimal study design, power to detect linkage and association, determining the most appropriate statistical methods and software, interpretation of statistical results and trouble shooting. We will also cover the basic principles of statistical inference, hypothesis testing, population and quantitative genetics and Mendelian inheritance. Our interactive and intensive educational program will enable one to better carry out sophisticated statistical analyses of genetic data, and will also improve one's interpretation and understanding of the results. All the software used is freely available, so that skills learned can be easily applied after the course.
Organization: Wellcome Trust Advanced Courses
11 July 2015 - 17 July 2015
Wellcome Trust Genome Campus
Cambridge, United Kingdom
Contact: Advanced Courses (advancedcourses@sanger.ac.uk)
Phone: 01223 6910
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