Course - Cold Spring Harbor, NY, United States
Over the last decade, large scale DNA sequencing has markedly impacted the practice of modern biology and is beginning to effect the practice of medicine. With the introduction of several advanced sequencing technologies, costs and timelines have been reduced by orders of magnitude, facilitating investigators to conceptualize and perform sequencing-based projects that heretofore were prohibitive. Furthermore, the application of these technologies to answer questions previously not experimentally approachable is broadening their impact and application.
This intensive 2 week course will explore applications of next generation sequencing technologies, with a focus on commercially available methods. Students will be instructed in the detailed operation of several revolutionary sequencing platforms, including sample preparation procedures, general data handling through pipelines, and in-depth data analysis. A diverse range of the types of biological questions enabled by next-generation sequencing technologies will be explored including DNA re-sequencing of known cancer genes to compare tumor and normal DNA, de novo DNA sequencing and assembly of bacterial genomes, RNA-sequencing, and others that are tailored to the student's research areas of interest. Guest lecturers will highlight their own applications of these revolutionary technologies.
Tue, Nov 11, 2014 - Sun, Nov 23, 2014
Cold Spring Harbor Laboratory, NY, United States
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