Mt Sinai Neuroscience Research Excellence Earns Strong NIH Funding

The Department of Neuroscience at New York's Mount Sinai School of Medicine comprises 25 research laboratories with total NIH funding for 2012 of $19.3M. Most labs are on the 9th Floor of the Icahn Medical Institute building on Madison Avenue. Neuroscience faculty may also receive support and engage in collaborative research through MSSM's Friedman Brain Institute, which coordinates brain and spinal cord research from departments and clinics across the medical school campus. In fact, the largest recipient of 2012 NIH funding at MSSM Neuroscience is Brain institute Director Eric J. Nestler, MD, PhD.

[The Nestler Lab at Mt. Sinai, courtesy of the Dept. of Neuroscience]

The Nestler Lab (above) studies the molecular mechanisms of drug addiction and depression, with funding from both the NIMH (National Institute of Mental Health) and NIDA (National Institute for Drug Addiction). Current projects total $4,961,151 from both NIH sources and include these studies:

• Molecular Studies of Cocaine Action in the Brain ($528K, with yearly funding since 1992)
• Molecular Neurobiology of Drug Addiction ($1.6M, with yearly funding since 1993)
• Neurotrophic Mechanisms in Opiate and Cocaine Action ($413K, with yearly funding since 2000)
• Pharmacological Actions of Antidepressant Treatments ($414K, with yearly funding since 1994)
• Epigenetic Mechanisms of Depression ($2M, new this year) 

[The Morrison Lab at Mt. Sinai, courtesy of the Dept. of Neuroscience]

Second in 2012 NIH funding from the Neuroscience Department is Dr. John H. Morrison, with $2,706,892. Dr. Morrison is also the Dean of Basic Sciences and the Graduate School of Biological Sciences at Mt. Sinai. The Morrison Lab (above) studies the neurobiology of aging, with these NIH/NIA funded projects:

• Glutamate Receptors in Aging Coritcal Circuits ($510K, funded yearly since 1987)
• Estrogen and the Aging Brain ($2.2M, funded yearly since 1999)

[The Schaeffer Lab at Mt. Sinai, courtesy of the Dept. of Neuroscience]

The third most-highly funded Neuroscience researcher in 2012 is Dr. Anne Schaefer, who is also the recipient of a 2012 NIH Director’s New Innovator Award worth $1.5M over 5 years. Dr. Schaefer received her PhD in 2004 and started The Schaefer Lab of Brain Epigenetics (above) in 2011 to study neuronal function in psychiatric and degenerative diseases. She is also currently a Seaver Fellow at the Friedman Brain Institute. Her NIH project, funded with $2.5M is:

• Cognate Microglia-Neuron Interaction and its Role in Inflammation

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