Researchers at the University of California, Los Angeles, have discovered a new stem cell that assists in repairing lung airways. The discovery is significant because the airways are vital in protecting the body from airborne toxins. The airways contain glands that defend the body by producing and then removing mucus, a process which cleanses the lungs of infectious agents and environmental toxins. The study's findings have major potential for advancement in the field of lung regeneration.
Dr. Brigitte Gomperts, a professor of hematology/oncology and senior author of the study said, "We're very excited that we found this population of cells because it will allow us to study mechanisms of diseases of the upper airway. For example, there currently are no treatments for excess mucus production... But if we can understand the mechanisms of how these stem cells repair the mucus glands, then we may be able to find a way to put the breaks on the system and prevent mucus over production."
(Courtesy of UCLA's JCCC)
According to the study, published in the June 27, 2011 issue of Stem Cells, the "ability to identify the stem cells and their regenerative ability has implications for the possible identification of novel therapeutics targets for airway diseases and potential cell-based therapies in the future."
The study was conducted by Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA.
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